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CHAPTER 1 Cells and Genomes Questions 1-1 Your friend studies the SARS virus and tells you that the SARS virus packages its genetic material as a positive-strand single-stranded RNA. A positive-strand RNA is an RNA molecule that can serve as […]

CHAPTER 10 Membrane Structure Questions 10-1 You are interested in studying the composition of lipid bilayers and how they are maintained. You discover two uncharacterized phospholipids, which you call PLX and PLZ. You decide to characterize the behavior of PLX […]

CHAPTER 11 Membrane Transport of Small Molecules and the Electrical Properties of Membranes Questions 11-1 Is the following statement true or false? Explain your answer. O2 is bigger than Mg2+ and thus will diffuse more slowly across a lipid bilayer. […]

CHAPTER 12 Intracellular Compartments and Protein Sorting Questions 12-1 You are studying a protein that normally resides in the plasma membrane. The organization of this protein is depicted in Figure Q12-1, where the gray boxes labeled A, B, and C […]

CHAPTER 13 Intracellular Vesicular Traffic Questions 13-1 You have a protein that has two transmembrane domains. The spacing of the transmembrane domains is shown as gray boxes in Figure Q13-1. The C-terminal domain of this protein is cytoplasmic. Figure Q13-1 […]

CHAPTER 14 Energy Conversion: Mitochondria and Chloroplasts Questions 14-1 You want to study the biochemical properties of the respiratory enzyme complexes required for oxidative phosphorylation. Your initial goal is to measure proton pumping by the NADH dehydrogenase complex. You mix […]

CHAPTER 15 Mechanisms of Cell Communication Questions 15-1 Your friend is trying to understand how the hormone cortisol affects kidney, liver, and bone cells by examining a set of cell lines derived from kidney cells, liver cells, and bone cells. […]

CHAPTER 16 The Cytoskeleton Questions 16-1 Actin-binding proteins can modify the properties of actin. You purify an actin– binding protein called Abp. You examine the effect of Abp on actin polymerization by measuring the kinetics of in vitro actin filament […]

CHAPTER 17 The Cell Cycle Questions 17-1 You want to study the cell cycle in fish embryo cells, in which the cell cycle length is about 30 min. You examine the amount of M-cyclin in these cells and see that […]

CHAPTER 18 Apoptosis Questions 18-1 You are working in a laboratory investigating the effects of new chemicals called X and Y that kill cells. To test whether X and Y cause necrosis or apoptosis, you briefly treat cultured cells with […]

CHAPTER 19 Cell Junctions, Cell Adhesion, and the Extracellular Matrix Questions 19-1 Your two friends are having an argument. Henry, who works in a lab studying signal transduction, claims that ligand–receptor interactions are higher affinity interactions than those between two […]

CHAPTER 2 Cell Chemistry and Biosynthesis Questions 2-1 A major goal of interplanetary research is to find evidence of water on other planets, in the search for extraterrestrial life. All known life requires water. A. Describe three properties of water […]

CHAPTER 20 Cancer Questions 20-1 Identify the two errors in this statement: “Cells from a benign lung tumor that has metastasized to the liver no longer make any lung-specific proteins.” 20-2 Carcinogenesis requires that a single cell or one of […]

CHAPTER 3 Proteins Questions 3-1 The table lists the average strengths of noncovalent bonds. Table Q3-1 Protein Lock binds to protein Key in a reaction with G° = –14 kcal/mol. When these proteins bind, 350 Å2 of the surface of […]

CHAPTER 4 DNA, Chromosomes, and Genomes Questions 4-1 Figure Q4-1 shows a hypothetical alignment of nucleotide sequences from two organisms. The bottom panel shows an alignment of large chromosomal regions, with black blocks representing DNA stretches of at least 500 […]

CHAPTER 5 DNA, Replication, Repair, and Recombination Questions 5-1 The mutation rate is about 1 mutation per 109 nucleotides per cell division in most organisms, from E. coli bacteria through nematode worms up to humans. You aspire to develop an […]

CHAPTER 6 How Cells Read the Genome: From DNA to Protein Questions 6-1 Consider an RNA molecule that forms part of an RNP. On the basis of an alignment of the nucleotide sequence of this RNA from several species and […]

CHAPTER 7 Control of Gene Expression Questions 7-1 Figure Q7-1 shows a DNA double helix and its nucleotide sequence. A. Indicate the major groove and the minor groove. B. A homodimeric helix–turn–helix protein binds to a DNA fragment containing this […]

CHAPTER 8 Manipulating Proteins, DNA, and RNA Questions 8-1 You have accidentally torn the labels off two tubes, each containing a different plasmid, and now do not know which plasmid is in which tube. Fortunately, you have restriction maps for […]

CHAPTER 9 Visualizing Cells Questions 9-1 Your friend has joined a lab that has a light microscope connected to a computer imaging system. A 30-inch monitor is attached to the computer. Your friend claims that because he can now enlarge […]