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What term is used to describe genetic exchange at equivalent positions along two
chromosomes with substantial DNA sequence homology?
What method might be used to study a knockout mouse that, by virtue of the lost gene
or genes, generates a lethal condition?
What is a transgenic organism?
Chronic myelogenous leukemia appears to be associated with a chromosomal
rearrangement. Which chromosome(s) is(are) involved, and what is the name of the
rearrangement?
Differentiate among the following types of genes: tumor-suppressor gene,
proto-oncogene, and oncogene.
How do mitochondria and chloroplasts determine phenotypes? Which characteristics of
mitochondria and chloroplasts allow such phenotypes to be inherited? Provide specific
examples to illustrate your response.
Given the accompanying table:
Where numbers 1 through 4 indicate four supplements that must be added to sustain
growth of the organism. Determine a possible metabolic pathway that would give the
results seen for the four mutant strains, A through D.
Name the three components of phenotypic variance.
It is presently believed that the asymmetric distribution of substances in the egg,
positioned by the mother, is responsible for establishing the determined state. Which
general term describes such molecular positioning?
Present an overview of two classical experiments that demonstrated that DNA is the
genetic material. Can RNA be the genetic material? Explain.
The process of error correction of mismatched bases carried out by DNA polymerases is
called ________.
In some cases, genes undergo amplification (local, multiple duplications) when
additional gene products are in high demand. Would you consider gene amplification as
a form of genetic regulation in eukaryotes? Explain your answer.
What method have farmers used for millennia to enhance food production in plants and
animals?
What is the term given to a random subset of individuals who are selected for
measurement in a particular study?
All other factors being equal, the renaturation of the three classes of complementary
nucleic acid sequences occurs in what order, from fastest to slowest?
Early in the twentieth century, Walter Sutton and Theodor Boveri noted that the
behavior of chromosomes during meiosis is identical to the behavior of genes during
gamete formation. They proposed that genes are carried on chromosomes, which led to
the basis of the ________.
How is a microarray used to scan for mutations in a genome?
A certain type of congenital deafness in humans is caused by a rare autosomal recessive
gene. In a mating involving a deaf man and a deaf woman, could some of the children
have normal hearing? Explain your answer.
