C) only I, II, and III
D) only II, III, and IV
The questions below refer to the following paragraph.
HIV’s genome of RNA includes the code for reverse transcriptase (RT), an enzyme that
acts early in infection to synthesize a DNA genome off of an RNA template. The HIV
genome also codes for protease (PR), an enzyme that acts later in infection by cutting
long viral polyproteins into smaller, functional proteins. Both RT and PR represent
potential targets for antiretroviral drugs. Drugs called nucleoside analogs (NA) act
against RT, whereas drugs called protease inhibitors (PI) act against PR.
Which of the following represents the treatment option most likely to avoid the
evolution of drug-resistant HIV (assuming no drug interactions or side effects)?
A) using a series of NAs, one at a time, and changed about once a week
B) using a single PI, but slowly increasing the dosage over the course of a week
C) using high doses of NA and a PI at the same time for a period not to exceed one day
D) using moderate doses of NA and two different PIs at the same time for several
months
Female birds lay their eggs, thereby facilitating flight by reducing weight. Which
‘strategy” seems most likely for female bats to use to achieve the same goal?