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Tightly curled hair is caused by a dominant autosomal gene in humans. If a
heterozygous curly-haired person marries a person with straight hair, what phenotypes
(and in what proportions) are expected in the offspring?
A color-blind woman with Turner syndrome (XO) has a father who is color blind.
Given that the gene for the color-blind condition is recessive and X-linked, provide a
likely explanation for the origin of the color-blind and cytogenetic conditions in the
woman.
Assume that one conducted a typical cloning experiment using a typical plasmid,
transformed an appropriate host bacterial strain, and plated the bacteria on an
appropriate X-gal medium. Blue and white colonies appeared. Which of the two types
of colonies, blue or white, would most likely contain the recombinant plasmid?
What is a cDNA molecule?
Albinism, lack of pigmentation in humans, results from an autosomal recessive gene
(a). Two parents with normal pigmentation have an albino child. What is the probability
that their next three children will be albino?
Maternal effects are cases of extrachromosomal inheritance in which the genotype of
the mother influences the phenotype of her immediate offspring in a non-Mendelian
manner. Provide a rationale for the molecular basis of a maternal effect.
Name the term used to describe the phenomenon in which a bacteriophage genome
incorporates its genome into the chromosome of the host.
List five general categories of mutation.
What evidence indicates that steroid hormones exert their influence at the level of
DNA?
How do VNTRs relate to DNA fingerprinting?
What is a form of recombination in bacteria that involves the F plasmid?
Can human genes be patented?
Provide a brief description of segment polarity genes, including their regulation and
their molecular and developmental effects.
What is the name of the process of selecting a specific group of organisms from an
initially heterogeneous population for future breeding purposes?
Deletions are chromosomal aberrations in which some portion of a chromosome is
missing. Describe a method using Drosophila deletions to determine the actual,
physical location of a gene.
Which human condition is caused by unrepaired UV-induced lesions?
Under what circumstance can an individual with Down syndrome have 46
chromosomes?
