Reserve Problems Chapter 14 Section 3 Problem 5
An article in Journal of Chemical Technology and Biotechnology [“A Study of Antifungal
Antibiotic Production by Thermomonospora sp MTCC 3340 Using Full Factorial Design” (2003,
Vol. 78, pp. 605-610)] considered the effects of several factors on antifungal activities. The
antifungal yield was expressed as Nystatin international units per cm3. Each treatment
combination was replicated three times. The results from carbon source concentration (glucose)
and incubation temperature factors follow.
(a) State the hypotheses of interest.
(b) Test your hypotheses with
. Find the P-values for temperature, carbon and
interaction. Which factors affect the antifungal activities?
(с) Using Fisher’s LSD method, compare the means of antifungal activity for the different
carbon source concentrations. Use
.
Find the standard error of the difference between two mean.
Find the largest difference in means of antifungal activity for the different carbon source
concentrations.
SOLUTION
(a)
,
at least one
(b)