________________________________________________ Chapter 48Diabetes Mellitus and Hypoglycemia 17
Introduction to Medical-Surgical Nursing, 6th ed.
Insulin Therapy (cont.)
• Insulin pump
• Needle is inserted subcutaneously in an appropriate part of the anatomy
TALKING POINTS:
• Consists of a battery–driven syringe with a long piece of tubing (usually made of Teflon)
that is attached to a small needle.
• One advantage of the external insulin pump is that patients do not have to use
intermediate- or long-acting insulins, with their uncertain peaks and valleys.
• What is an “artificial pancreas?”
Oral Hypoglycemic Agents
• If patients with type 2 DM unable to control blood glucose with nutrition and exercise,
provider may prescribe oral hypoglycemics
• Sulfonylureas (three generations), alpha-glucosidase inhibitors, biguanides,
thiazolidinediones,
D-phenylalanines, meglitinides
• Dipeptidyl peptidase-4 inhibitor agents
TALKING POINTS:
• What interventions may be required if the blood glucose rises above 200 mg/dL?
Injectable Medications to Treat Diabetes
• Pramlintide slows gastric emptying and suppresses appetite
• Exenatide lowers blood glucose levels by increasing insulin secretion, suppressing
postprandial glucagon secretion, slows gastric emptying, suppressing the appetite
• Complex dosing schedules requiring injections before each meal
• Expensive; not covered by many insurance companies
• Another noninsulin injection, Liraglutide, stimulates insulin production while suppressing
hepatic glucose output, helps with weight loss
Self-Monitoring of Blood Glucose
• Allows patients to monitor blood glucose levels to regulate diet, exercise, and medication
regimen to remain euglycemic
• Portable electronic glucose meters have largely replaced other methods of
self-monitoring
TALKING POINTS:
• The self-monitoring of blood glucose levels is seen as the greatest breakthrough in
managing diabetes since the advent of insulin.
• What should premeal plasma glucose levels be? Bedtime glucose levels?