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e1
QUESTIONS
1. Compare the assays used to assess corrosivity and
irritancy in skin substitute test systems.
2. Discuss the advantages of cryopreservation in the
blasts and keratinocytes to skin test systems?
4. What value may skin test systems have in understand-
ing disease?
5. Discuss the potential value and problems of geneti-
cellular skin substitutes by comparison with ones
containing live cells.
9. Discuss the use of skin substitutes in the treatment
of genetic disease.
10. What mechanisms can you put forward as a basis
11. What is the value of skin substitutes in the treatment
of acute wounds?
12. Cells of the skin are capable of sorting themselves
to form a dermal/epidermal structure in which the
13. Discuss the contrast between growth conditions
suitable for CHO cells for recombinant protein
CHAPTER II.6.12
Tissue-Engineered Skin Substitutes
