Fibromyalgia affects about 2% of the U.S. population. Its primary symptoms are chronic
pain, difficulty sleeping and fatigue that is not relieved by sleep. Other reported
symptoms include: jaw clenching at night, dryness of mouth and eyes, an increased
need to urinate, irritable bowels, muscle numbness and tingling, and headaches.
1. Several researchers have proposed that fibromyalgia results from failed regulation of
part of the autonomic nervous system. If this is true, failed regulation of which
division of the autonomic nervous system could account for these symptoms?
Explain your reasoning.
The sympathetic system is responsible for arousal and energy generation while the
2. To test their ideas, the researchers recorded heart rate of both controls and
individuals with fibromyalgia for 24-hour periods of normal activity. They ob-
served that patients with fibromyalgia showed greatly elevated heart rates both while
active and asleep. Does the addition of this information change or support the
hypothesis you developed in 1 above?
Given this information, the primary symptoms appear to be the result of
330 Activity 49.1
49.1 Test Your Understanding