Chapter 01 – Taking Risks and Making Profits within the Dynamic Business Environment
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Some amateur inventors remain wary of Quirky since submitting a concept to the site automati-
cally grants intellectual property rights to the company. Nevertheless, Quirky needs to retain full owner-
ship of an idea if it is to develop it to the furthest extent. In fact, the creator of the Pivot Power knew noth-
ing about electrical engineering when he submitted the basic blueprint of his idea. Most Quirky designs
are fully realized by the company after what amounts to a spark of inspiration from one of its users. The
company doesn’t just shine in the R&D room and on the factory floor, though. Besides connections with a
number of major retailers, Quirky also recently entered into a partnership with General Electric. The two
companies will share patents and release products under a shared Quirky + G.E. brand.iii
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SOCIAL ENTREPRENEURSHIP: IMPROVING WORLD HEALTH WITH-
OUT PROFITS
Knowing that Victoria Hale was a pharmaceutical scientist, a friend called her, desperate. Their
13-year-old daughter had been diagnosed with a deadly form of cancer called Ewing’s sarcoma. The
daughter’s doctors were offering little hope, and the cancer was spreading fast. Could Hale help? With the
aid of a former FDA colleague, she began searching for experimental compounds that might offer any ray
of hope. They found two substances that had shown initial promise in fighting the cancer, but both were
sitting idle on laboratory shelves. No one was working to develop the compounds into drugs. The cancer
was too rare to create an attractive market for new treatments.
The young girl lost her battle with cancer, and Hale was determined to change things. She created
OneWorldHealth, the first U.S. nonprofit pharmaceutical company.
Hale identified five disease categories that she believed could benefit from an aggressive drug
development effort, but would not be profitable. Her plan was this: Find research on these diseases that
had already been conducted, but nothing had been done because the drug would not be profitable. She
would then persuade the pharmaceutical company to donate the information to her in return for tax write-
offs. Finally, she would seek funding from foundations and others to make those drugs available.
Hale got $4.7 million from the Bill and Melinda Gates Foundation for researching diseases in the
developing world. She also negotiated deals with the World Health Organization and the National Insti-
tutes of Health to do some clinical trials. Hale hopes that she can sell some drugs at a profit in order to
continue her work.
As scientists and companies heard about the organization’s efforts, many began calling to say
“We’ve got something you might be interested in.” Many scientists are also volunteering their time and
expertise. Hale doesn’t find this surprising. “Most pharmaceutical researchers got into the business be-
cause they wanted to ease suffering and save lives. Systems may be flawed, but most people want to do
the right thing,” says Hale.
All organizations need money to operate. One of the major sources of money is investors who
give money to firms in order to make a profit. Those firms have to be profitable. Nonprofit organizations
usually rely on the donations from others to keep operating. Often that money comes from profit-making
companies, like Celera, who are concerned about disease prevention, but can’t stay in business unless
they make a profit. Hale has found a way to link these organizations. iv
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MOBILE ENTREPRENEURS OPERATE ON THE GO
For many years, the famous phrase “location, location, location” served as one of the most unfail-
ing maxims in the business lexicon. But as the digital age has broken down borders and streamlined