6. Which of the following neuroendocrine abnormalities is implicated in depression?
Hypersecretion of cortisol
An exaggerated response of thyrotropin (TRH) to infusion of thyroid-releasing
hormone
Increased inhibitory response of glucocorticoids to dexamethasone
7. The clinician has chosen to prescribe an SSRI instead of a tricyclic antidepressant (TCA) for a
patient fitting the diagnostic criteria for depression. Which of the following is NOT true
concerning SSRIs in comparison to tricyclic antidepressants?
SSRIs are more effective than TCAs.
SSRIs take less time to work than TCAs.
SSRIs have a more favorable side-effect profile than TCAs.
SSRIs are not lethal in overdose.
8. After discontinuing fluoxetine, how long must a person wait before starting a monoamine
oxidase inhibitor?
9. It is important to educate patients with depression and their family members about reporting
signs of increasing depression and suicidal thoughts. This is especially true during which time
period?
Prior to the antidepressant reaching therapeutic levels
As the mood lifts in response to antidepressant treatment
During dosage or medication adjustments
After the patient reveals suicidal thoughts or plans
10. A patient is experiencing extrapyramidal side effects from his antipsychotic medications. The
clinician would most likely take which of the following approaches to treating these side
effects?
Give the patient a “drug holiday” until the symptoms resolve and then restart the
medication.
Switch the patient to a different antipsychotic.
Treat the patient with anticholinergics.
Treat the patient with anticonvulsants.
11. According to Kübler-Ross, the stages of grief occur in which order?