Chapter 14
350 Chapter 14 ■ MULTIPLE CHOICE QUIZ
Chapter Fourteen
MULTIPLE CHOICE QUIZ
Name: ______________________________
In the box write the letter of the choice that is the definition of the term or best answers the
question. There is only one correct answer for each question.
1. Formation of lymph: ………………………
A. Lymphocytopenia
B. Lymphadenitis
C. Lymphedema
D. Lymphopoiesis
E. Lymphoid
2. Interstitial fluid contains or is: ………..
A. Antibodies produced by white blood cells
B. Red and white blood cells
C. Found in the spaces between cells and
becomes lymph when it enters lymph
capillaries
D. Connective tissue
E. Blood clotting factors
3. All of the following are part of the
immune system EXCEPT: ………………
A. Lymphocytes
B. Platelets
C. Monocytes
D. Phagocytes
E. Antibodies
4. All of the following describe areas of
lymph node concentration EXCEPT: …
A. Inguinal
B. Axillary
C. Bone marrow
D. Mediastinal
E. Cervical
5. Atopy is: ………………………………………
A. An early stage of AIDS
B. A hypersensitivity or allergic state
C. A type of lymphoma
D. A disease found in tropical areas
E. Acute infectious disease caused by
Epstein-Barr virus
6. Helper or suppressor cells are
types of: ………………………………………
A. B cells
B. T cells
C. Platelets
D. Antigens
E. Antibiotics
7. Examples of immunoglobulins: ……….
A. IgA, IgG, IgE
B. Monocytes
C. Lymphocytes
D. Hepatocytes
E. Clotting factors
8. Oropharyngeal lymph tissue: …………..
A. Spleen
B. Thymus
C. Bone marrow
D. Tonsils
E. Adenoids
9. Mediastinal T-cell producer: …………….
A. Spleen
B. Thymus
C. Bone marrow
D. Tonsils
E. Adenoids
10. Nasopharyngeal lymph tissue: ………….
A. Spleen
B. Thymus
C. Bone marrow
D. Tonsils
E. Adenoids
11. Abdominal organ that filters erythrocytes
and activates lymphocytes: ………………
A. Spleen
B. Thymus
C. Bone marrow
D. Tonsils
E. Adenoids
12. Produces lymphocytes and monocytes
and all other blood cells: …………………
A. Spleen
B. Thymus
C. Bone marrow
D. Tonsils
E. Adenoids
Chapter 14 ■ MULTIPLE CHOICE QUIZ 351
13. Cytotoxic cells
are: …………………………………………….
A. B cell lymphocytes
B. T-cell lymphocytes
C. Platelets
D. Thrombocytes
E. Eosinophils
14. Interferons and interleukins are: ………
A. Gamma globulins
B. Interstitial fluid
C. Antiviral proteins produced by T-cell
lymphocytes
D. Produced by B-cell lymphocytes
E. Helper cells
15. Slight increase in numbers of
lymphocytes: ………………………………..
A. Lymphocytopenia
B. Lymphopoiesis
C. Lymphoid
D. Lymphocytosis
E. Lymphedema
16. Pertaining to poison: ……………………..
A. Necrotic
B. Hypoxic
C. Cyanotic
D. Toxic
E. Stenotic
17. Computerized x-ray imaging in the
transverse plane: …………………………..
A. CT scan
B. Lymphangiogram
C. Ultrasonography
D. MRI
E. Lymphadenectomy
18. HIV is: ………………………………………..
A. A malignancy associated with AIDS
B. A drug used to treat AIDS
C. The virus that causes AIDS
D. The test used to detect AIDS
E. A type of lymphoma
19. Malignant tumor of lymph nodes: …….
A. Sarcoidosis
B. Lymphedema
C. Hodgkin lymphoma
D. Hypersplenism
E. Lymphocytopenia
20. Viral infection causing blisters on
skin of lips, nose, or genitals: ………….
A. Kaposi sarcoma
B. Herpes simplex
C. Cryptococcus
D. Toxoplasmosis
E. Pneumocystis jiroveci pneumonia
21. Cancer arising from the lining cells of
capillaries, producing bluish red skin
nodules: ………………………………………
A. Kaposi sarcoma
B. Herpes simplex
C. Cryptococcus
D. Toxoplasmosis
E. Pneumocystis jiroveci pneumonia
22. Major lung infection with fever, cough,
chest pain, and sputum. Treatment is
with Bactrim ………………………………..
A. Kaposi sarcoma
B. Herpes simplex
C. Cryptococcus
D. Toxoplasmosis
E. Pneumocystis jiroveci pneumonia
23. Protozoal (parasitic) infection associated
with AIDS. Produces pneumonitis,
hepatitis, and encephalitis: ………………
A. Kaposi sarcoma
B. Herpes simplex
C. Cryptococcosis
D. Toxoplasmosis
E. Pneumocystis jiroveci pneumonia
24. Fungal infection associated with AIDS.
Involves brain and meninges, lungs,
and skin: ……………………………………..
A. Kaposi sarcoma
B. Herpes simplex
C. Cryptococcosis
D. Toxoplasmosis
E. Pneumocystis jiroveci pneumonia
352 Chapter 14 ■ VOCABULARY QUIZ
Chapter Fourteen
VOCABULARY QUIZ
Name: ______________________________
(textbook pages 555–557)
A. Match the following vocabulary terms with their meanings below:
acquired immunity B cell dendritic cell
adenoids cervical nodes helper T cell
antigen cytokines
axillary nodes cytotoxic T cell
1. Lymph nodes in the neck region _____________________________________________________
2. Substance that the body recognizes as foreign and evokes an
immune response _________________________________________________________________
3. Production of antibodies and lymphocytes in response to
exposure to an antigen _____________________________________________________________
4. Lymphocyte that aids B cells in recognizing antigens and stimulating antibody production
(CD4+ cell) _______________________________________________________________________
5. Mass of lymphatic tissue in the nasopharynx ____________________________________________
6. Cell (specialized macrophage) that digests foreign cells and helps B and T cells recognize and
mark antigens for destruction _______________________________________________________
7. T lymphocyte that directly kills antigens (CD8+ cell) _____________________________________
8. Lymph nodes in the armpit __________________________________________________________
9. Proteins that aid and regulate the immune response _____________________________________
10. Lymphocyte that originates in the bone marrow and transforms into a plasma cell to
secrete antibodies _________________________________________________________________
Chapter 14 ■ VOCABULARY QUIZ 353
B. Match the following vocabulary terms with their meanings below:
immunity inguinal nodes lymph capillaries
immunoglobulins interferons and interleukins lymph node
immunotherapy interstitial fluid mesenteric nodes
lymphoid organs lymph paraaortic nodes
1. Thin, watery fluid found within lymphatic vessels ________________________________________
2. Tiniest lymphatic vessels ____________________________________________________________
3. Proteins (cytokines) secreted by T cells to aid and regulate the
immune response _________________________________________________________________
4. Antibodies that are secreted by plasma cells in response
to the presence of an antigen ________________________________________________________
5. Body’s ability to resist foreign organisms and toxins (immune response) _____________________
6. Lymph nodes in the groin ___________________________________________________________
7. Stationary, solid lymphatic tissue along lymph vessels ____________________________________
8. Fluid in the spaces between cells _____________________________________________________
9. Lymph nodes, spleen, and thymus gland; tissue through
which lymph travels _______________________________________________________________
10. Use of immune cells and antibodies or vaccines to treat
and prevent disease ________________________________________________________________
11. Lymph nodes associated with a major artery ____________________________________________
12. Lymph nodes in the intestinal region __________________________________________________
354 Chapter 14 ■ VOCABULARY QUIZ
C. Match the following vocabulary terms with their meanings below:
lymph vessel natural immunity suppressor T cell
macrophage plasma cell tolerance
mediastinal nodes right lymphatic duct
monoclonal antibody spleen
1. Lymphocyte that produces and secretes antibodies _______________________________________
2. Carrier of lymph throughout the body _________________________________________________
3. Lymph nodes in the area between the lungs in the thoracic cavity __________________________
4. The ability of T cells (T lymphocytes) to recognize and accept the body’s
own antigens as “self” ______________________________________________________________
5. Large phagocyte found in lymph nodes and other tissues of the body ________________________
6. Antibody produced in a laboratory to attack antigens and destroy cells _______________________
7. Organ near the stomach that produces, stores, and eliminates blood cells ____________________
8. Protection that an individual is born with to fight infection ________________________________
9. Lymphocyte that inhibits the activity of B and T cells (Treg) _______________________________
10. Large lymphatic vessel in the chest that receives lymph from the upper right portion
of the body _______________________________________________________________________
Chapter 14 ■ VOCABULARY QUIZ 355
D. Match the following vocabulary terms with their meanings below:
cell-mediated immunity thymus gland vaccination
humoral immunity tonsils vaccine
thoracic duct toxin
1. Mass of lymphatic tissue in the back of the oropharynx ___________________________________
2. Organ in the mediastinum that conditions T cells to react
to foreign cells ____________________________________________________________________
3. A poison _________________________________________________________________________
4. Weakened or killed microorganisms, toxins, or other proteins (antigens) given to provoke an
immune response _________________________________________________________________
5. Large lymphatic vessel in the chest that receives lymph from below the diaphragm and from
the left side of the body above the diaphragm ___________________________________________
6. Exposure of an individual to a foreign protein (antigen) that provokes an immune
response _________________________________________________________________________
7. Involves B cells that produce antibodies _______________________________________________
8. Involves T cells that respond to antigens and destroy them ________________________________
356 Chapter 14 ■ TERMINOLOGY QUIZ
Chapter Fourteen
TERMINOLOGY QUIZ
Name: ______________________________
(textbook pages 558–559)
A. Complete the following terms to match the definitions below; select from the following
medical word parts:
-cyt/o -globulin -pathy
-cytosis -itis -penia
-ectomy -megaly -poiesis
-edema -oid
1. Deficiency of lymphocytes: lympho ___________________________________________________
2. Antibody (protein) secreted by plasma cells: immuno _____________________________________
3. Formation of lymph: lympho ________________________________________________________
4. Increase in numbers of lymphoctyes: lympho ___________________________________________
5. Swelling within tissue spaces (collection of interstitial fluid): lymph ________________________
6. Organs that are part of the lymph system: lymph __________________________________ organs
7. Disease of lymph nodes: lymphadeno __________________________________________________
8. Enlargement of the spleen: spleno ____________________________________________________
9. Inflammation of lymph nodes: lymphaden ______________________________________________
10. Excision of the spleen: splen _________________________________________________________
B. Select from the following terms to match the definitions below:
anaphylaxis hypersplenism thymectomy
asplenia immunosuppression toxic
autoimmune disease interstitial fluid
1. Removal of the thymus gland ________________________________________________________
2. Exaggerated or unusual hypersensitivity to previously encountered proteins
or antigens _______________________________________________________________________
3. Pertaining to a poison ______________________________________________________________
4. Syndrome marked by enlarged spleen, anemia, blood cell destruction _______________________
5. Liquid that bathes and surrounds cells ________________________________________________
6. Abnormal production of antibodies against normal body tissues ____________________________
7. Normal reaction of the immune system to foreign agents is impaired ________________________
8. Condition of absence of the spleen ____________________________________________________
Chapter 14 ■ PATHOLOGY QUIZ 357
Chapter Fourteen
PATHOLOGY QUIZ
Name: ______________________________
(textbook pages 559–563)
A. Match the following pathologic conditions and associated terms with their meanings below:
acquired immunodeficiency Kaposi sarcoma reverse transcriptase inhibitor
syndrome opportunistic infections wasting syndrome
CD4+ cells protease inhibitor
human immunodeficiency
virus
1. Infections diseases associated with AIDS _______________________________________________
2. Drug that treats AIDS by blocking the production of a proteolytic enzyme that creates new
viral pieces for HIV ________________________________________________________________
3. Malignant condition associated with AIDS; colored skin nodules appear ______________________
4. Infectious agent that causes AIDS ____________________________________________________
5. Weight loss, decrease in muscular strength, appetite and mental activity _____________________
6. Drug that treats AIDS by blocking an enzyme needed to make copies of HIV __________________
7. Group of symptoms associated with suppression of the immune system; infections, new
growths, and neurologic problems ____________________________________________________
8. Helper T cells that are destroyed by the AIDS virus _______________________________________
B. Match the following pathologic terms with their definitions below:
allergen Hodgkin lymphoma severe combined
allergy multiple myeloma immunodeficiency disease
atopic dermatitis non-Hodgkin lymphoma thymoma
1. Malignant tumor of a lymphoid organ in the mediastinum ________________________________
2. Malignant tumor of bone marrow cells (plasma cells) _____________________________________
3. Substance capable of causing a specific hypersensitivity reaction in the body __________________
4. Group of malignant tumors involving lymphoid tissue; follicular and large cell are
types ____________________________________________________________________________
5. Malignant tumor of lymph tissue in the spleen and lymph nodes; Reed-Sternberg cell is
often found on microscopic analysis __________________________________________________
6. Hypersensitivity or allergic state involving an inherited predisposition; inflammation of the
skin _____________________________________________________________________________
7. Infants are born with deficiency of B and T cells _________________________________________
8. Abnormal hypersensitivity acquired by exposure to an antigen _____________________________
358 Chapter 14 ■ LABORATORY TESTS, CLINICAL PROCEDURES
Chapter Fourteen
LABORATORY TESTS, CLINICAL
PROCEDURES, AND
ABBREVIATIONS QUIZ
Name: ______________________________
(textbook pages 564–565)
A. Match the following with their definitions below:
CD4+ cell count immunoelectrophoresis viral load test
computed tomography MoAb
ELISA Treg
1. Measures the amount of AIDS virus in the bloodstream ___________________________________
2. Measures the number of helper T cells in the bloodstream of patients
with AIDS ________________________________________________________________________
3. X-ray imaging produces cross-sectional and other views of
anatomic structures _______________________________________________________________
4. Test that separates immunoglobulins __________________________________________________
5. Screening test to detect anti-HIV antibodies in the bloodstream ____________________________
6. Antibody produced in a laboratory to attack antigens and destroy cells _______________________
7. Suppressor T cell that inhibits the activity of B and T cells ________________________________
Chapter 14 ■ LABORATORY TESTS, CLINICAL PROCEDURES 359
B. On the line provided, give meanings for the following abbreviations, then write each
abbreviation next to its explanation below:
1. AIDS __________________________________________________________________________
2. NHL __________________________________________________________________________
3. HAART __________________________________________________________________________
4. HD __________________________________________________________________________
5. HIV __________________________________________________________________________
6. IgA __________________________________________________________________________
7. KS __________________________________________________________________________
8. SCID __________________________________________________________________________
a. Use of combinations of drugs that are effective against AIDS
b. Malignant tumor of lymph tissue in spleen and lymph nodes; Reed-Sternberg cell is
often found on microscopic analysis
c. Malignant condition associated with AIDS; dark-colored skin nodules appear
d. Group of malignant tumors involving lymphoid tissue; follicular and large cell are types
e. Infants are born with a deficiency of B and T cells
f. Infectious agent that causes AIDS
g. Group of symptoms associated with suppression of the immune system
h. Antibody in the blood
360 Chapter 14 ■ EXERCISE QUIZ
Chapter Fourteen
EXERCISE QUIZ
Name: ______________________________
The questions on this quiz have all been taken from the exercises at the end of this chapter.
A. Give the name of the structure or fluid from its meaning below:
1. Stationary lymph tissue along the path of lymph vessels __________________________________
2. Large thoracic lymph vessel draining lymph from lower and
left side of the body ________________________________________________________________
3. Organ near the stomach that produces, stores, and eliminates blood cells ____________________
4. Mass of lymph tissue in the nasopharynx _______________________________________________
5. Organ in the mediastinum that produces T-cell lymphocytes _______________________________
6. Tiniest of lymph vessels _____________________________________________________________
7. Large lymph vessel in the chest that drains lymph from right
upper part of the body ______________________________________________________________
8. Fluid that lies between cells and becomes lymph as it enters
lymph capillaries __________________________________________________________________
B. Give the locations of the following lymph nodes:
9. inguinal nodes _______________________ 11. cervical nodes __________________________
10. axillary nodes ________________________ 12. mediastinal nodes _______________________
C. Match the term in Column I with its description in Column II
Column I Column II
13. immunoglobulins __________ A. Lymphocytes that inhibit the activity of B and
T cells; Treg
14. toxins __________ B. Antibodies—IgG, IgE, IgM, IgD
15. helper T cells __________ C. Lymphocytes that aid B cells and stimulate
T cells.
16. cytotoxic cells __________ D. Poisons (antigens)
17. interferons __________ E. Lymphocyte that directly kills antigens.
18. plasma cells __________ F. Proteins secreted by T cells
19. suppressor T cells __________ G. Lymphocytes that secrete antibodies
Chapter 14 ■ EXERCISE QUIZ 361
D. Build medical terms:
20. removal of the spleen ______________________________________________________________
21. inflammation of lymph glands (nodes) _________________________________________________
22. tumor of the thymus gland __________________________________________________________
23. disease of lymph glands (nodes) ______________________________________________________
24. formation of lymph ________________________________________________________________
25. deficiency of lymph cells ____________________________________________________________
26. pertaining to poison _______________________________________________________________
27. enlargement of the spleen ___________________________________________________________
E. Match the following terms with their meanings below:
AIDS Hodgkin lymphoma lymphoid organs
allergen hypersplenism thymectomy
anaphylaxis lymphedema
28. Syndrome marked by enlargement of the spleen and associated with anemia, leukopenia,
and thrombocytopenia _____________________________________________________________
29. An extraordinary hypersensitivity to a foreign protein; marked by hypotension, shock,
respiratory distress ________________________________________________________________
30. An antigen capable of causing allergy (hypersensitivity) ___________________________________
31. Disorder in which the immune system is suppressed by exposure to HIV _____________________
32. Removal of a mediastinal organ ______________________________________________________
33. Malignant tumor of lymph nodes and spleen marked by Reed-Sternberg cell identified in
lymph nodes ______________________________________________________________________
34. Tissues that produce lymphocytes—spleen, thymus, tonsils, and adenoids ____________________
35. Swelling of tissues due to interstitial fluid accumulation __________________________________
F. Give meanings for the following terms or abbreviations:
36. HIV _____________________________________________________________________________
37. Histo ____________________________________________________________________________
38. KS ______________________________________________________________________________
39. PCP _____________________________________________________________________________
40. CT scan __________________________________________________________________________
41. Toxo ____________________________________________________________________________
362 Chapter 14 ■ EXERCISE QUIZ
G. Match the following terms with their meanings below:
ELISA opportunistic infections
immunoelectrophoresis zidovudine
helper T cells
42. White blood cells that are destroyed by HIV _____________________________________________
43. Test to separate immunoglobulins ____________________________________________________
44. Drug used to treat AIDS by blocking the growth of AIDS virus _____________________________
45. Test used to detect anti-HIV antibodies ________________________________________________
46. Group of infectious diseases associated with AIDS _______________________________________
Chapter 14 ■ DICTATION AND COMPREHENSION QUIZ 363
Chapter Fourteen
DICTATION AND
COMPREHENSION QUIZ
Name: ______________________________
A. Dictation of Terms
1. ____________________________________ 11. ______________________________________
2. ____________________________________ 12. ______________________________________
3. ____________________________________ 13. ______________________________________
4. ____________________________________ 14. ______________________________________
5. ____________________________________ 15. ______________________________________
6. ____________________________________ 16. ______________________________________
7. ____________________________________ 17. ______________________________________
8. ____________________________________ 18. ______________________________________
9. ____________________________________ 19. ______________________________________
10. ____________________________________ 20. ______________________________________
B. Comprehension of Terms: Match the number of the above term with its meaning below.
Malignant tumor associated with AIDS; appears as bluish red skin nodules
Hypersensitive or allergic state involving hereditary predisposition
Disease condition of lymph nodes
Enlargement of the spleen
Collection of lymph tissue in the groin
Substance capable of causing a specific hypersensitivity reaction in the body
A drug that is used to treat AIDS by blocking the production of an enzyme
An exaggerated or unusual hypersensitivity to a foreign protein
Lymphocyte that aids B cells and cytotoxic T cells in recognizing antigens and stimulating antibody
production: also called CD4+ cell
Antiviral proteins secreted by T cells
Malignant tumor of a gland in the chest
Found within lymphatic vessels and surrounding tissues throughout the body
Lymphatic tissue in the oropharynx
Collection of lymph tissue under the arm (armpit)
Proteins that aid and regulate the immune response
Malignant tumor of lymph nodes and tissue
Antibodies such as IgG, IgA, IgD that are secreted by plasma cells
Introduction of altered antigens to produce an immune response
Repression of the immune response
Fluid collects within the spaces between cells secondary to lymph vessel obstruction