Chapter 13
316 Chapter 13 ■ MULTIPLE CHOICE QUIZ
Chapter Thirteen
MULTIPLE CHOICE QUIZ
Name: ______________________________
In the box write the letter of the choice that is the definition of the term or best answers the
question. There is only one correct answer for each question.
1. White blood cell with reddish
granules; numbers increase in
allergic reactions: ………………………….
A. Lymphocyte
B. Eosinophil
C. Neutrophil
D. Erythrocyte
E. Basophil
2. Protein threads that form the basis of
a clot: ………………………………………….
A. Fibrinogen
B. Globulin
C. Hemoglobin
D. Thrombin
E. Fibrin
3. Method of separating out plasma
proteins by electrical charge: ……………
A. Plasmapheresis
B. Hematocrit
C. Electrophoresis
D. Coagulation time
E. Leukapheresis
4. Foreign material that invades the
body: …………………………………………..
A. Neutrophils
B. Macrophages
C. Antibodies
D. Antigens
E. Granulocytes
5. Pigment produced from hemoglobin
when red blood cells are destroyed: …..
A. Serum
B. Albumin
C. Globulin
D. Plasma
E. Bilirubin
6. An undifferentiated blood cell is called
a(an): ………………………………………….
A. Granulocyte
B. Segmented cell
C. Hematopoietic stem cell
D. Thrombocyte
E. Lymphocyte
7. Anticoagulant found in the
blood: ………………………………………….
A. Heparin
B. Prothrombin
C. Thrombin
D. Gamma globulin
E. Vitamin B12
8. A disorder of red blood cell
morphology is: ……………………………..
A. Multiple myeloma
B. Poikilocytosis
C. Monocytosis
D. Acute myelocytic leukemia
E. Hemochromatosis
9. Deficiency in numbers of white
blood cells: …………………………………..
A. Neutropenia
B. Hypochromia
C. Leukocytosis
D. Chronic lymphoid leukemia
E. Spherocytosis
10. Immature red blood cell: …………………
A. Thrombocyte
B. Monoblast
C. Segmented
D. Erythroblast
E. Megakaryoblast
11. Derived from bone marrow: …………….
A. Myeloid
B. Lymphoid
C. Granulocytopenic
D. Polymorphonuclear
E. Phagocytic
12. Breakdown of recipient’s red blood
cells when incompatible bloods are
mixed: …………………………………………
A. Erythrocytosis
B. Hemolysis
C. Embolism
D. Anticoagulation
E. Erythropoiesis
Chapter 13 ■ MULTIPLE CHOICE QUIZ 317
13. Sideropenia occurs causing deficient
production of hemoglobin: ………………
A. Pernicious anemia
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia
E. Thalassemia
14. Reduction in red cells due to
excessive cell destruction: ……………….
A. Pernicious anemia
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia
E. Thalassemia
15. Failure of blood cell production due to
absence of formation of cells in the
bone marrow: ……………………………….
A. Pernicious anemia
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia
E. Thalassemia
16. Inherited defect in ability to produce
hemoglobin: …………………………………
A. Pernicious anemia
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia
E. Thalassemia
17. Lack of mature red cells due to inability to
absorb vitamin B12 into the body:
A. Pernicious anemia
B. Iron deficiency anemia
C. Aplastic anemia
D. Hemolytic anemia
E. Thalassemia
18. Excessive deposits of iron throughout
the body: ……………………………………..
A. Polycythemia vera
B. Cooley anemia
C. Purpura
D. Hemochromatosis
E. Thrombocytopenia
19. Symptoms of pallor, shortness of
breath, infection, bleeding gums,
predominance of immature and
abnormally functioning leukocytes,
and low numbers of mature
neutrophils in a young child may
indicate a likely diagnosis of: …………..
A. Sickle cell anemia
B. Hemostasis
C. Acute lymphoid leukemia
D. Chronic lymphoid leukemia
E. Hemoglobinopathy
20. Excessive bleeding caused by
congenital lack of factor VIII or IX: …..
A. Autoimmune thrombocytopenic purpura
B. Granulocytosis
C. Polycythemia vera
D. Erythremia
E. Hemophilia
21. Venous blood is clotted in a test tube:
A. Hematocrit
B. White blood cell differential
C. Erythrocyte sedimentation rate
D. Coagulation time
E. Red blood cell morphology
22. Sample of blood is spun in a test tube
so that red cells fall to the bottom and
percentage of RBCs is taken: …………..
A. Hematocrit
B. White blood cell differential
C. Erythrocyte sedimentation rate
D. Coagulation time
E. Red blood cell morphology
23. Blood smear is examined to determine
the shape or form of cells: ………………
A. Hematocrit
B. White blood cell differential
C. Erythrocyte sedimentation rate
D. Coagulation time
E. Red blood cell morphology
318 Chapter 13 ■ MULTIPLE CHOICE QUIZ
24. Leukocytes are stained and counted
under a microscope to see numbers
of mature and immature forms: ………..
A. Hematocrit
B. White blood cell differential
C. Erythrocyte sedimentation rate
D. Coagulation time
E. Red blood cell morphology
25. Venous blood is collected;
anticoagulant added and the distance
cells fall in a period of time is
determined: ………………………………….
A. Hematocrit
B. White blood cell differential
C. Erythrocyte sedimentation rate
D. Coagulation time
E. Red blood cell morphology
26. Blood protein that maintains the
proper proportion and concentration
of water in blood: …………………………..
A. Bilirubin
B. Prothrombin
C. Fibrinogen
D. Albumin
E. Globulin
27. Swelling; fluid leaks out into tissue
spaces: ………………………………………..
A. Petechiae
B. Edema
C. Ecchymoses
D. Dyscrasia
E. Autologous transfusion
28. IgM, IgG, IgA, IgD, IgE: …………………
A. Megakaryocytes
B. Eosinophils
C. Neutrophils
D. Stem cells
E. Immunoglobulins
29. Symptoms of disease return: …………..
A. Palliative
B. Relapse
C. Hemoglobinopathy
D. Remission
E. Spherocytosis
30. Relieving symptoms, but not
curing disease: ……………………………..
A. Coagulopathy
B. Hemostasis
C. Hematocrit
D. Palliative
E. Myelopoiesis
Chapter 13 ■ VOCABULARY QUIZ 319
Chapter Thirteen
VOCABULARY QUIZ
Name: ______________________________
(textbook pages 512–513)
A. Match the following vocabulary terms with their meanings below:
albumin bilirubin eosinophil
antibody coagulation erythrocyte
antigen differentiation erythropoietin
basophil electrophoresis fibrin
1. Orange-yellow pigment in bile; formed by the breakdown of hemoglobin _____________________
2. Blood protein that maintains the proper amount of water in the blood _______________________
3. White blood cell containing granules that stain red; associated with allergic
reactions ________________________________________________________________________
4. Blood clotting ____________________________________________________________________
5. Method of separating serum proteins by electrical charge _________________________________
6. Foreign substance that stimulates the production of an antibody ___________________________
7. Red blood cell ____________________________________________________________________
8. Change in structure and function of a cell as it matures __________________________________
9. White blood cell containing granules that stain blue; associated with release
of histamine and heparin ___________________________________________________________
10. Hormone secreted by the kidneys that stimulates red blood cell formation ___________________
11. Immunoglobulin produced by lymphocytes to combat specific antigens ______________________
12. Protein threads that form the basis of a blood clot _______________________________________
B. Match the following terms with their definitions below:
fibrinogen hemolysis macrophage
globulins heparin plasma
granulocyte immune reaction
hemoglobin lymphocyte
1. Monocyte that migrates from the blood to tissue spaces; a phagocyte ________________________
2. Response of the immune system to foreign invasion ______________________________________
3. Mononuclear leukocyte that produces antibodies ________________________________________
4. Anticoagulant found in blood and tissue cells ___________________________________________
5. Destruction or breakdown of blood ___________________________________________________
6. Liquid portion of the blood __________________________________________________________
320 Chapter 13 ■ VOCABULARY QUIZ
7. Blood protein containing iron _______________________________________________________
8. Plasma protein that is converted to fibrin in the clotting process ___________________________
9. White blood cell with numerous dark-staining granules; neutrophil, basophil, and
eosinophil _______________________________________________________________________
10. Plasma proteins; alpha, beta, and gamma are examples ___________________________________
C. Match the following terms with their meanings below:
hematopoietic stem cell plasmapheresis serum
immunoglobulin platelet (thrombocyte)
neutrophil reticulocyte
1. White blood cell containing granules and formed in bone marrow __________________________
2. Small blood fragment that collects at sites of injury to begin
the clotting process ________________________________________________________________
3. Unspecialized cell that gives rise to mature, specialized forms; found in bone
marrow __________________________________________________________________________
4. Removal of plasma from withdrawn blood by centrifuge __________________________________
5. Plasma minus clotting proteins and cells _______________________________________________
6. Protein with antibody activity; IgG, IgA, IgM, IgD, and IgE are examples _____________________
7. Immature erythrocyte ______________________________________________________________
Chapter 13 ■ TERMINOLOGY QUIZ 321
Chapter Thirteen
TERMINOLOGY QUIZ
Name: ______________________________
(textbook pages 514–516)
A. Match the following terms with their meanings given below:
anticoagulant eosinophil hemolysis
basophil erythrocytopenia hypochromic
coagulopathy hematocrit
cytology hemoglobinopathy
1. White blood cell with dark-staining blue granules; releases
heparin and histamine _____________________________________________________________
2. Pertaining to a deficiency in color (of red blood cells) ____________________________________
3. White blood cell with dark-staining red granules;
elevated in allergic reactions _________________________________________________________
4. Disorder marked by abnormality in hemoglobin _________________________________________
5. Destruction or breakdown of blood fired blood cells) ______________________________________
6. Study of cells _____________________________________________________________________
7. Percentage of red blood cells in a volume of blood _______________________________________
8. Disorder or disease of clotting _______________________________________________________
9. Deficiency of red blood cells _________________________________________________________
10. Substance that stops blood clotting ___________________________________________________
B. Complete the medical terms from the definitions given:
1. Deficiency of white blood cells: leukocyto ______________________________________________
2. Immature bone marrow cell: myelo ___________________________________________________
3. Study of the shape (of cells): ____________________________________________________ ology
4. Deficiency of neutrophils: neutro _____________________________________________________ .
5. Abnormal formation of bone marrow: _________________________________________ dysplasia
6. White blood cell with one large nucleus: ___________________________________________ cyte
7. Cell that eats or swallows bacteria and debris: _______________________________________ cyte
8. Deficiency of iron: ____________________________________________________________ penia
9. Deficiency of platelets: _________________________________________________________ penia
10. Pertaining to a white blood cell with multilobed (shaped) nucleus: ____________________ nuclear
322 Chapter 13 ■ TERMINOLOGY QUIZ
C. Match the following terms with their meanings below:
erythroblast microcytosis poikilocytosis
hemoglobin monoblast spherocytosis
leukapheresis plasmapheresis
macrocytosis plateletpheresis
1. Immature white blood cell __________________________________________________________
2. Abnormal condition of small red blood cells ____________________________________________
3. Immature red blood cell ____________________________________________________________
4. Abnormal condition of red blood cells that are irregularly shaped ___________________________
5. Plasma is separated from other parts of the blood ________________________________________
6. Abnormal condition of rounded red blood cells __________________________________________
7. Abnormal condition of large red blood cells ____________________________________________
8. White blood cells are separated from other parts of the blood ______________________________
9. Clotting cells are separated from other parts of the blood _________________________________
10. Iron-containing protein in red blood cells ______________________________________________
D. Complete the medical terms from the definitions given:
1. Antibody-containing protein in blood: immuno _________________________________________
2. Therapy used to dissolve (breakdown) clots: thrombo _______________________________ therapy
3. Resembling bone marrow cells: myel __________________________________________________
4. Deficiency of granulocytes: granulo ___________________________________________________
5. Increase in numbers of neutrophils: neutro ____________________________________________
6. Abnormal condition of clotting: thromb _______________________________________________
7. Formation of blood: hemato _________________________________________________________
8. Deficiency of all types of blood cells: pan _______________________________________________
9. Formation of bone marrow cells: myelo ________________________________________________
10. Stopping or controlling the flow of blood: hemo _________________________________________
Chapter 13 ■ PATHOLOGY QUIZ 323
Chapter Thirteen
PATHOLOGY QUIZ
Name: ______________________________
(textbook pages 517–522)
A. Match the following conditions with their definitions below:
aplastic anemia mononucleosis sickle cell anemia
hemochromatosis pernicious anemia thalassemia
hemolytic anemia polycythemia vera
hemophilia purpura
1. Multiple pinpoint hemorrhages and accumulation of blood under the skin ___________________
2. General increase in red blood cells (erythremia) _________________________________________
3. Excess iron deposits throughout the body ______________________________________________
4. Hereditary condition characterized by abnormal crescent shape of erythrocytes and by
destruction of red blood cells ________________________________________________________
5. Inherited defect in the ability to produce hemoglobin, usually seen in persons of Mediterranean
background ______________________________________________________________________
6. Infectious disease marked by increased numbers of leukocytes and enlarged cervical lymph
nodes ___________________________________________________________________________
7. Reduction in red cells due to excessive destruction _______________________________________
8. Failure of blood cell production due absence of formation of
bone marrow cells _________________________________________________________________
9. Excessive bleeding caused by hereditary lack of factor VIII or factor IX necessary for blood
clotting __________________________________________________________________________
10. Lack of mature erythrocytes caused by inability to absorb vitamin B12 into the
body ____________________________________________________________________________
B. Name the types of leukemia from their descriptions and abbreviations below:
1. Abnormal numbers of relatively mature lymphocytes predominate in the bone marrow, lymph
nodes, and spleen (CLL) ____________________________________________________________
2. Immature granulocytes predominate in the bone marrow (AML) ___________________________
3. Both mature and immature granulocytes are present in the bone marrow and bloodstream
(CML) ___________________________________________________________________________
4. Immature lymphocytes predominate in the bone marrow and lymph nodes
(ALL) ___________________________________________________________________________
324 Chapter 13 ■ PATHOLOGY QUIZ
C. Match the following terms with their meanings below:
dyscrasia iron deficiency anemia relapse
ecchymoses multiple myeloma remission
eosinophilia palliative
Epstein-Barr virus petechiae
1. Tiny purple or red flat spots on the skin as a result of hemorrhages _________________________
2. Causative agent in mononucleosis ____________________________________________________
3. Large blue or purplish patches on the skin (bruises) _____________________________________
4. Sideropenia is the cause of this condition ______________________________________________
5. Any disease of the blood or bone marrow _______________________________________________
6. Disappearance of signs and symptoms of disease _________________________________________
7. Relieving, but not curing disease _____________________________________________________
8. Disease symptoms and signs reappear _________________________________________________
9. Malignant neoplasm of bone marrow __________________________________________________
10. Increase in numbers of granulocytes associated with allergic conditions _____________________
Chapter 13 ■ LABORATORY TESTS AND CLINICAL PROCEDURES QUIZ 325
Chapter Thirteen
LABORATORY TESTS AND
CLINICAL PROCEDURES QUIZ
Name: ______________________________
(textbook pages 522–526)
A. Match the following laboratory test with its definition below:
antiglobulin test erythrocyte sedimentation rate red blood cell count
bleeding time hematocrit red blood cell morphology
coagulation time hemoglobin test
complete blood count platelet count
1. Microscopic examination of a stained blood smear to determine
the shape of RBCs _________________________________________________________________
2. Time required for blood to stop flowing from a tiny puncture wound ________________________
3. Determination of number of blood cells, hemoglobin and hematocrit, and other RBC
values ___________________________________________________________________________
4. Test for the presence of antibodies that coat and damage erythrocytes _______________________
5. Time required for venous blood to clot in a test tube _____________________________________
6. Total amount of hemoglobin in a sample of peripheral blood _______________________________
7. Speed at which erythrocytes settle out of plasma ________________________________________
8. Number of erythrocytes per cubic millimeter or microliter of blood _________________________
9. Number of thrombocytes per cubic millimeter or microliter of blood ________________________
10. Percentage of erythrocytes in a volume of blood _________________________________________
B. Select from the following laboratory tests and clinical procedures to match the definitions
below:
1. apheresis 5. prothrombin time
2. blood transfusion 6. white blood cell count
3. bone marrow biopsy 7. white blood cell differential
4. hematopoietic stem cell transplantation
A. __________ Microscopic examination of a core of bone marrow removed with a needle
B. __________ Separation of blood into component parts and removal of a select portion from the blood
C. __________ Percentages of the different types of leukocytes in the blood
D. __________ Whole blood or cells are taken from a donor and infused into a patient
E. __________ Test of the ability of blood to clot
F. __________ Peripheral stem cells from a donor are administered into a recipient
G. __________ Number of leukocytes per cubic millimeter of blood
326 Chapter 13 ■ ABBREVIATIONS QUIZ
Chapter Thirteen
ABBREVIATIONS QUIZ
Name: ______________________________
(textbook pages 526–527)
A. On the line provided, give meanings for the following abbreviations, then write each
abbreviation next to its explanation below:
1. ALL _____________________________________________________________________________
2. AML ____________________________________________________________________________
3. ASCT ____________________________________________________________________________
4. baso ____________________________________________________________________________
5. BMT ____________________________________________________________________________
6. CBC ____________________________________________________________________________
7. CLL ____________________________________________________________________________
8. CML ____________________________________________________________________________
9. diff. _____________________________________________________________________________
10. EBV ____________________________________________________________________________
a. __________ Granulocytic white blood
cells
b. __________ Abnormal numbers of
relatively mature lymphocytes predominate
c. __________ A patient is his or her own
donor for stem cell transplant
d. __________ Abnormal numbers of
immature granulocytes predominate
e. __________ Recipient receives donation
of bone marrow
f. __________ Percentages of different types
of WBCs are given
g. __________ Cause of mononucleosis
h. __________ Mature and immature
granulocytes are present in the marrow and
bloodstream
i. __________ Calculation of numbers of
blood cells, hemoglobin, hematocrit and
red cell values
j. __________ Immature lymphocytes
(lymphoblasts) predominate
Chapter 13 ■ ABBREVIATIONS QUIZ 327
B. On the line provided, give meanings for the following abbreviations, then write each
abbreviation next to its explanation below:
1. eos _____________________________________________________________________________
2. EPO ____________________________________________________________________________
3. ESR ____________________________________________________________________________
4. Fe ______________________________________________________________________________
5. GVHD _____ ______________________________________________________________________
6. Hct _____________________________________________________________________________
7. Hgb ____________________________________________________________________________
8. IgA, IgD, IgE _____________________________________________________________________
9. lymph cells _______________________________________________________________________
10. mono ___________________________________________________________________________
a. __________ Percentage of red cells in a
volume of blood
b. __________ Stimulates red blood cell
formation
c. __________ Element that makes up
hemoglobin
d. __________ Mononuclear white blood
cell; phagocyte
e. __________ Granulocytic white blood cell
elevated in allergic reactions
f. __________ Speed at which erythrocytes
settle out of plasma
g. __________ White blood cells that make
antibodies; mononuclear agranulocyte
h. __________ Protein found in red blood
cells; carries oxygen
i. __________ Immune reaction of donor’s
cells to recipient’s tissues
j. __________ Proteins that have antibody
activity
328 Chapter 13 ■ ABBREVIATIONS QUIZ
a. __________ Carries oxygen in the
bloodstream
b. __________ Time it takes for red cells to
settle out of plasma
c. __________ Neutrophils; segmented
leukocytes
d. __________ Time it takes for blood to clot
e. __________ Determination of numbers of
leukocytes
f. __________ Levels of a blood protein
and percentage of red blood cells are
determined
g. __________ Preleukemic condition
C. On the line provided, give meanings for the following abbreviations, then write each
abbreviation next to its explanation below:
1. H and H _________________________________________________________________________
2. MDS ____________________________________________________________________________
3. polys ____________________________________________________________________________
4. PT ______________________________________________________________________________
5. RBC _____________________________________________________________________________
6. sed rate _________________________________________________________________________
7. WBC ____________________________________________________________________________
Chapter 13 ■ EXERCISE QUIZ 329
Chapter Thirteen
EXERCISE QUIZ
Name: ______________________________
A. Match the following cells with their meanings below:
basophil hematopoietic stem cell neutrophil
eosinophil lymphocyte platelet
erythrocyte monocyte
1. red blood cell _____________________________________________________________________
2. white blood cell; phagocyte and precursor of a macrophage ________________________________
3. thrombocyte _____________________________________________________________________
4. bone marrow cell; gives rise to many types of blood cells __________________________________
5. leukocyte formed in lymph tissue; produces antibodies ___________________________________
6. leukocyte with dense reddish granules; associated with allergic reactions ____________________
7. leukocyte (poly) formed in bone marrow and having neutral-staining
granules _________________________________________________________________________
8. leukocyte whose granules have an affinity for basic stain; releases histamine and
heparin __________________________________________________________________________
B. Give medical terms for the following descriptions:
9. liquid portion of blood ______________________________________________________________
10. hormone secreted by the kidney to stimulate erythrocyte production
in bone marrow ___________________________________________________________________
11. proteins in plasma; can be separated into alpha, beta, and gamma types ______________________
12. plasma protein that maintains the proper amount of water in blood _________________________
13. proteins made by lymphocytes in response to antigens in the blood _________________________
C. Divide the following terms into component parts, and give the meaning of the term:
14. leukocytopenia ____________________________________________________________________
15. myelopoiesis _____________________________________________________________________
16. anticoagulant _____________________________________________________________________
17. thrombolytic _____________________________________________________________________
330 Chapter 13 ■ EXERCISE QUIZ
D. Match the following terms concerning red blood cells with their meanings:
erythroblast hypochromia poikilocytosis
erythropoiesis macrocytosis polycythemia vera
hemolysis microcytosis
18. irregularity in shape _______________________________________________________________
19. immature red cells _________________________________________________________________
20. reduction of hemoglobin (“color”) ____________________________________________________
21. increase in numbers of small cells ____________________________________________________
22. erythremia _______________________________________________________________________
23. increase in numbers of large cells ____________________________________________________
24. formation of red cells ______________________________________________________________
25. destruction of red cells _____________________________________________________________
E. Describe the problem in the following forms of anemia:
26. sickle cell anemia _________________________________________________________________
27. aplastic anemia ___________________________________________________________________
28. thalassemia ______________________________________________________________________
F. Give the meanings for the following abbreviations and blood dyscrasias:
29. CLL _____________________________________________________________________________
30. AML ____________________________________________________________________________
31. autoimmune thrombocytopenic purpura _______________________________________________
32. hemophilia _______________________________________________________________________
G. Match the term in Column I with its meaning in Column II:
Column I Column II
33. relapse ___________________________ A. Relieving, but not curing
34. remission _________________________ B. Deficiency of all blood cells
35. purpura __________________________ C. Increase in numbers of granulocytes; seen in
allergic conditions
36. pancytopenia ______________________ D. Symptoms of disease return
37. palliative _____ _____________________ E. Multiple pinpoint hemorrhages; blood
accumulates under the skin.
38. eosinophilia _______________________ F. Separation of blood into its components
39. apheresis _________________________ G. Symptoms of disease disappear
Chapter 13 ■ EXERCISE QUIZ 331
H. Match the following laboratory test or clinical procedure with its description:
autologous transfusion Coombs test platelet count
bleeding time erythrocyte sedimentation rate red blood cell morphology
bone marrow biopsy hematocrit WBC differential
coagulation time hematopoietic stem cell transplantation
40. A stained blood smear is examined to determine the shape of individual
red blood cells ____________________________________________________________________
41. Measures the percentage of red blood cells in a volume of blood ____________________________
42. Determines the number of clotting cells per cubic millimeter ______________________________
43. Ability of venous blood to clot in a test tube ____________________________________________
44. Measures the speed at which erythrocytes settle out of plasma _____________________________
45. Determines the numbers of different types of WBCs ______________________________________
46. Determines the presence of antibodies in infants of Rh-negative women or patients with
autoimmune hemolytic anemia ______________________________________________________
47. Undifferentiated blood cells from a donor are infused into a patient being treated for leukemia
or aplastic anemia _________________________________________________________________
48. Time it takes for a small puncture wound to stop bleeding _________________________________
49. Needle is introduced into the bone marrow cavity, and a small amount of marrow is aspirated
and then examined under the microscope ______________________________________________
50. Blood is collected from and later reinfused into the same patient ___________________________