48.
A lipid bilayer is formed by self assembly of _________.
A)
triglycerides
B)
saturated fatty acids
C)
phospholipids
D)
unsaturated fatty acids
E)
B & C
Ans:
C
49.
Which of the following is a correct description of the following compound?
O
H
H
H
HO
A)
triglyceride
B)
steroid
C)
phospholipid
D)
prostaglandin
E)
terpene
Ans:
B
50.
In naturally occurring steroids mostly the B-C ring fusion is ______and the C-D ring
fusion is ______.
A)
cis, trans
B)
cis, cis
C)
trans, cis
D)
trans, trans
E)
none of these
51.
In androsterone the A-B ring fusion is ______and the B-C ring fusion is ______.
O
H
H
H
H
HO
A
B
C
A)
cis, trans
B)
cis, cis
C)
trans, cis
D)
trans, trans
E)
none of these
Ans:
D
Ans:
D
52.
Which of the following is a correct numbering of the steroid nucleus?
A)
I
B)
II
C)
III
D)
IV
E)
none of these
Ans:
C
53.
Predict the product when cholesterol is treated with acetyl chloride in presence of
pyridine.
HO
H
H H
H
H
acetyl chloride
pyridine
54.
Predict the major product when cholesterol is treated with peroxy acetic acid.
HO
H
H H
H
H
peroxy acetic acid
55.
Predict the major product when cholesterol is treated with hydrogen in the presence of a
palladium catalyst.
HO
H
H H
H
H
H2/Pd
56.
Which one of the following is a male sex hormone?
A)
estrone
B)
androsterone
C)
cortisone
D)
lanosterol
E)
all of these
Ans:
B
57.
Which one of the following is a female sex hormone?
A)
estrone
B)
androsterone
C)
cortisone
D)
lanosterol
E)
nandrolone
Ans:
A
58.
Which one of the following is a used to treat the inflammatory condition caused by
arthritis?
A)
norethindrone
B)
androsterone
C)
cortisone
D)
lanosterol
E)
stanozolol
Ans:
C
59.
Which of the following are secreted by the adrenal cortex?
A)
cortisone
B)
androsterone
C)
esrone
D)
lanosterol
E)
estradiol
Ans:
A
60.
Predict the product when testosterone is treated with PCC.
61.
Predict the product when estradiol is treated with excess NaH followed by excess
bromopropane.
OH
H
HH
HO
1. NaH
2. bromopropane
excess
62.
Draw a chair conformation for the following compound.
O
H
HH
HO
H
63.
Prostaglandins are made up of ___ carbon atoms.
A)
14
B)
16
C)
18
D)
20
E)
22
64.
Which of the following is not a characteristic of prostaglandins?
A)
five membered cyclic ring
B)
carbonyl group
C)
two side chains
D)
hydroxyl group
E)
six membered monocyclic ring
Ans:
E
65.
Which one of the following is a correct representation of PGCs?
O
R
R’
O
R
R’
O
R
R’
O
R
R’
HO
OH
R
R’
O
III III IV V
A)
I
B)
II
C)
III
D)
IV
E)
V
Ans:
B
Ans:
D
66.
Which one of the following is a correct representation of PGFs?
O
R
R’
O
R
R’
OH
R
R’
HO
OH
R
R’
O
III III IV V
O
R
R’
HO
A)
I
B)
II
C)
III
D)
IV
E)
V
67.
Which one of the following is a correct classification of the following compound?
O
HO
O
OH
HO
A)
steroid
B)
prostaglandin
C)
triglyceride
D)
terpene
E)
lecithin
Ans:
B
Ans:
D
68.
Which one of the following is not classified as an eicosanoid?
A)
leukotrienes
B)
prostaglandins
C)
thromboxanes
D)
prostacyclins
E)
cortisone
69.
Aspirin blocks the biosynthesis of which of the following eicosanoids?
A)
leukotrienes
B)
prostaglandins
C)
thromboxanes
D)
prostacyclins
E)
C & D
Ans:
B
70.
Following is the structure for PGF2What structural feature is represented by 2?
OH
HO
O
OH
HO
A)
2 represents the number of double bonds
B)
represents the trans relationship between the two OH groups
C)
represents the trans relationship between the side chains
D)
A & C
E)
A & B
Ans:
E
Ans:
E
71.
Which of the following are synthesized from arachidonic acid?
A)
leukotrienes
B)
prostaglandins
C)
thromboxanes
D)
prostacyclins
E)
all of these
72.
Which one of the following is a precursor for the synthesis of prostaglandins?
A)
arachidonic acid
B)
linoleic acid
C)
cholesterol
D)
linolenic acid
E)
all of these
Ans:
A
73.
Lipids containing repeated isoprene units are called________.
A)
cephalins
B)
terpenes
C)
eicosanoids
D)
steroids
E)
none of these
Ans:
B
Ans:
E
74.
Which one of the following compounds is classified as a sesquiterpene?
H
O
III III IV
A)
I
B)
II
C)
III
D)
IV
E)
all of these
75.
Citral is best classified as a ___________.
H
O
Citral
A)
monoterpene
B)
diterpene
C)
sesquiterpene
D)
triterpene
E)
tetraterpene
Ans:
A
Ans:
A
76.
Following is the structure of capsanthin found in capsicum. Which of the following is a
correct classification of capsanthin?
O
OH
HO
A)
monoterpene
B)
diterpene
C)
sesquiterpene
D)
triterpene
E)
tetraterpene
77.
How many isoprene units does the following compound have?
COH
O
A)
1
B)
2
C)
3
D)
4
E)
5
Ans:
D
Ans:
E
78.
Farnesol isolated from Lily of the Valley flowers, has the following structure. How
many isoprene units Farnesol
OH
A)
1
B)
2
C)
3
D)
4
E)
5
79.
Following is the structure of zingiberene found in ginger. Identify the isoprene units in
zingiberene.
Ans:
C
80.
Identify the isoprene units in partheniol
HO
81.
Identify the isoprene units in manool.
OH
82.
Identify the isoprene units in cedrol found in cedar.
OH
83.
Identify the isoprene units in squalene.
84.
Which of the following are the building blocks of terpenes?
OPP OPP OPP OPP
III III IV
OPP
V
A)
I & III
B)
II & III
C)
I & IV
D)
II & V
E)
II & IV
Ans:
A