50.
Provide the structures of the products in the following reaction sequence.
APCC B(CH3)2NH C
1. BH3
2. H2O2, NaOH/H2OH2SO4, NaBH3CN
51.
Provide the structures of the products in the following reaction sequence.
APCC BC
H3O+
H2SO4, NaBH3CN
H
N
52.
Predict the product for the following reaction.
CN
O
1. H2 / Pt
2. H3O
53.
Predict the product for the following reaction sequence.
Cl
O
AlCl3
(CH3)2NH
H2SO4, NaBH3CN
O
N
NO
N
OH
N
III III IV
A)
I
B)
II
C)
III
D)
IV
E)
none of these
Ans:
D
54.
Provide the reagents necessary to carry out the following conversion.
Cl
NHCCH2CH3
Cl
55.
Provide the reagents necessary to carry out the following conversion.
NH2
NO2
56.
Predict the major product for the following reaction.
NH2
1. excess CH3I
2. Ag2O, H2O
heat
N(CH3)2OH
III III IV
A)
I
B)
II
C)
III
D)
IV
E)
I & III
57.
Predict the major product for the following reaction.
1. excess CH
3
I
2. Ag
2
O, H
2
O
NH2
heat
III III IV
A)
I
B)
II
C)
III
D)
IV
E)
I & III
Ans:
A
Ans:
B
58.
Predict the major product for the following reaction.
N
1. excess CH3I
2. Ag2O, H2O
heat
NNNN
N
III III IV V
A)
I
B)
II
C)
III
D)
IV
E)
V
59.
Predict the major product for the following reaction.
1. excess CH3I
2. Ag2O, H2O
Nheat
Ans:
E
60.
Predict the major product for the following reaction.
1. excess CH3I
2. Ag2O, H2O
NH2
heat
61.
Provide the reagents necessary to carry out the following conversion.
NH2
A
O
O
D
HO
NH2
BC
62.
Provide the reagents necessary to carry out the following conversion.
NO2
NH2
NO2
Cl
63.
Provide the reagent A, necessary to carry out the following conversion.
NH2
Br
Br
NaNO2/HCl
< 50C
OCH3
Br
Br
A
A)
H3PO2
B)
HCN
C)
H2O
D)
CH3OH, heat
E)
NaOCH3
64.
Provide the reagent A, necessary to carry out the following conversion.
NH2
Br
Br
A
Br
Br
NaNO2/HCl
< 50C
Cl Cl
A)
Br2/FeBr3
B)
CuBr
C)
NaOH
D)
H3PO2
E)
H3PO4
65.
Which one of the following is the best synthesis for 3,5-dibromotoluene?
A)
toluene, Br2/FeBr3 excess
B)
1. p-toluidine, Br2/ FeBr3;
2. NaNO2/HCl, <5°C
3. H3PO2
C)
1. Toluene, HNO3/H2SO4
2. NH3
3. NaNO2/HCl, <5°C
4. CuBr
D)
m-dibromobenzene, CH3Cl/AlCl3
E)
m-bromotoluene, HNO3, H2SO4
2. Fe/HCl
3. NaNO2/HCl, <5°C
4. CuBr
Ans:
B
Ans:
D
66.
Provide the reagents necessary to carry out the following conversion.
COH
Cl
O
67.
Provide the reagents necessary to carry out the following conversion.
OCH3
CCH2CH3
68.
Provide the reagents necessary to carry out the following conversion.
OCH2CH3
Br
69.
Provide the reagents necessary to carry out the following conversion.
OH
NO2
70.
Provide the reagents necessary to carry out the following conversion.
OH