Chapter 07 – How Cells Harvest Energy
38. A biochemist wants to control the initial substrate-level phosphorylation that occurs in the
tracheal cells of grasshoppers once glucose has crossed the plasma membrane. He has access
to the following inhibitors: Rotenone – an electron transport chain inhibitor, Oligomycin – an
ATP synthase inhibitor, and TLN-232, an inhibitor of glycolysis. Which inhibitor should he
use to slow down initial substrate-level phosphorylation that occurs once glucose has crossed
the plasma membrane?
Chapter 07 – How Cells Harvest Energy
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
Gather Content
What do you already know about substrate-level phosphorylation during cellular
respiration? What other information is related to the question?
Choose Answer
Do you have all the information needed to determine which inhibitor would have the
biggest impact on substrate-level phosphorylation?
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 07 – How Cells Harvest Energy
39. To form NADH from NAD+, two electrons and a proton are removed from an organic
molecule. What term best describes the reaction in which electrons and a proton are removed
from an organic molecule?
40. Aerobic respiration involves the transfer of many electrons from glucose to electron
carriers such as NAD+ over a series of multiple steps. Ultimately though, it is the reaction of
glucose with oxygen to generate carbon dioxide, water and energy. Why doesn’t glucose react
directly with oxygen in cells?
Chapter 07 – How Cells Harvest Energy
41. Why is the energy generated from the catabolism of sugars and other macromolecules
ultimately harnessed to generate ATP?
42. When substrate-level phosphorylation occurs, it means that:
43. What is the net number of ATP generated directly during glycolysis per molecule of
glucose?
Chapter 07 – How Cells Harvest Energy
44. The Krebs cycle occurs in the mitochondria. There are nine biochemical reactions
involved in the Krebs cycle, and they are highly ordered. Select the correct order. (Note:
These are abbreviated and do not show NAD, ADP, ATP, or FAD.)
45. How many oxidation reactions occur during the Krebs cycle?rev:
02_07_2014_QC_44516
Chapter 07 – How Cells Harvest Energy
46. What would be the ATP yield for a molecule that is catabolized to form one molecule of
pyruvate in a eukaryotic cell?
Chapter 07 – How Cells Harvest Energy
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
Gather Content
What do you already know about ATP yield from pyruvate during cellular respiration?
What other information is related to the question?
Chapter 07 – How Cells Harvest Energy
Choose Answer
Do you have all the information needed to calculate the ATP yield from pyruvate?
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 07 – How Cells Harvest Energy
47. What is the oxidized form of the most common electron carrier that is needed for both
glycolysis and the Krebs cycle?
Chapter 07 – How Cells Harvest Energy
48. Many of the antiviral drugs currently used to treat HIV/AIDS also interfere with an
enzyme that helps mitochondria multiply. Treatment can therefore result in a decrease in the
number of mitochondria found in certain tissues. Given this information, what might you
expect to see in patients treated with antiviral drugs?
Chapter 07 – How Cells Harvest Energy
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
What do you already know about which cellular respiration processes occur in
mitochondria? How would a reduction in mitochondria affect the ability of the cell to
harvest energy? What other information is related to the question?
Choose Answer
Chapter 07 – How Cells Harvest Energy
Do you have all necessary information to determine the outcome on respiration from
taking antiviral drugs?
Reflect on Process
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 07 – How Cells Harvest Energy
Chapter 07 – How Cells Harvest Energy
49. Cytochromes contain a heme group similar to that in hemoglobin. The iron atom (Fe) in
the center of the group can be oxidized and reduced. If someone was suffering from iron
deficiency anemia, what stage of cellular respiration would be most affected?
Chapter 07 – How Cells Harvest Energy
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
Gather Content
What do you already know about redox reactions and when they take place during
cellular respiration? What other information is related to the question?
Choose Answer