Hall: Guyton and Hall Textbook of Medical Physiology, 12th Edition
Chapter 74: Introduction to Endocrinology
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1. Some cells secrete chemicals into the extracellular fluid that act on cells in the same
tissue. Which of the following refer to this type of regulation?
A. Neural
B. Endocrine
C. Neuroendocrine
D. Paracrine
E. Autocrine
2. If a radioimmunoassay is properly conducted and the amount of radioactive hormone
bound to antibody is low, this would indicate which of the following?
A. Plasma levels of endogenous hormone are high
B. Plasma levels of endogenous hormone are low
C. More antibody is needed
D. Less radioactive hormone is needed
3. An example of neuroendocrine secretion is the release of which of the following?
A. Somatostatin
B. Cortisol
C. Growth hormone
D. Prolactin
E. ACTH
4. Which of the following is an example of paracrine hormonal regulation?
A. Corticotropin releasing hormone: ACTH secretion
B. ACTH: cortisol secretion
C. Somatostatin: growth hormone secretion
D. Somatostatin: glucagon secretion
E. TSH: T4 secretion
5. Which of the following hormones is largely unbound to plasma proteins?
A. Aldosterone
B. T4
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C. Oxytocin
D. Estradiol
E. Progesterone
6. Which of the following hormones is not stored in its endocrine-producing gland?
A. T4
B. PTH
C. Aldosterone
D. ACTH
E. Insulin
7. Which of the following is true regarding hormone binding to plasma proteins?
A. It increases in the plasma clearance of the hormone
B. It increases the half-life of the hormone
C. It increases hormonal activity
D. It is uncommon for steroid hormones
E. It is uncommon for thyroid hormones
8. Which of the following peptide-second messengers are incorrectly paired?
A. Glucagon:cAMP
B. Insulin:cAMP
C. TSH:cAMP
D. ACTH:cAMP
E. ADH (V2 receptor):cAMP
9. Which of the following statements about peptide or protein hormones is usually true?
A. They have longer half-lives than steroid hormones
B. They have receptors on the cell membrane
C. They have a slower onset of action than both steroid and thyroid hormones
D. They are not highly stored in endocrine producing glands
10. Which of the following hormones does not activate G protein-linked receptors when
producing its predominate physiological effects?
A. TSH
B. Glucagon
C. ACTH
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D. ADH
E. Aldosterone