Chapter 07 – How Cells Harvest Energy
27. Arsenic poisoning can lead to organ failure and death. Though arsenic can inhibit or
interfere with a number of cellular enzymes, arsenic poisoning is thought to be mainly due to
indirect inhibition of enzymes involved in both pyruvate oxidation and the Krebs cycle. As a
result, this compound must be able to enter which cellular compartment?
Clarify Question
What is the key concept addressed by the question?
What type of thinking is required?
Gather Content
What do you already know about pyruvate oxidation and the Krebs cycle? What other
information is related to the question?
Choose Answer
Do you have all necessary information to determine where arsenic poisoning would have
its greatest impact within the cell?