Hall: Guyton and Hall Textbook of Medical Physiology, 12th Edition
Chapter 61: Cerebral Blood Flow, Cerebrospinal Fluid, and Brain Metabolism
Test Bank
1. Which of the following best describes the major function of cerebrospinal fluid?
A. Cerebrospinal fluid is a major controller of brain glucose metabolism
B. Cerebrospinal fluid delivers nutrients to deep brain structures
C. Cerebrospinal fluid serves a protective role by cushioning the brain inside the bony
vault of the skull
D. All of the above are good descriptors of cerebrospinal fluid
2. Which of the following statements are correct?
A. The uptake of glucose into the brain is not insulin-dependant
B. The increase in cerebral blood flow induced by CO2 is mediated by an increase in
hydrogen ion concentration
C. The brain accounts for approximately 15% of the total body metabolism and is highly
oxygen-dependant
D. All of the above
3. At mean arterial pressure levels between 140 mmHg and 170 mmHg, blood flow to the
brain:
A. Varies with the level of arterial pressure
B. Is constant and not dependant on pressure
C. Is independent of arterial pressure
D. Is inversely proportional to arterial pressure
4. An increase in pCO2 from 40 mmHg to 80 mmHg would cause brain blood flow to:
A. Decrease by 50 percent
B. Increase by 100 percent
C. Increase by 50 percent
D. Increase by 25 percent
5. Which of the following statements best describes the anaerobic capacity of the brain?
A. The brain can function well under anaerobic conditions because of its ability to use
lactic acid as an energy source
B. The brain has very little anaerobic capacity
Test Bank
61-2
C. The brain can function well under anaerobic conditions until the glycogen stores are
depleted
D. Both A and C are correct
6. Cerebrospinal fluid:
A. Is produced by the choroid plexus of the lateral ventricles
B. Is produced by the arachnoid villi
C. Is absorbed by the aqueduct of Sylvius
D. Is absorbed by the fourth ventricle
7. A patients pO2 is measured at 20 mmHg. What neurological effects would be seen in this
patient?
A. Agitation and nervousness
B. Normal responsiveness
C. Comatose or unresponsive
D. Somnolent but responsive to stimuli
8. The total volume of cerebrospinal fluid in an adult human nervous system is
approximately:
A. 150 mL
B. 500 mL
C. 50 mL
D. 300 mL
9. The total amount of cerebrospinal fluid produced each day by the choroid plexus of an
adult human is approximately?
A. 150 mL
B. 500 mL
C. 50 mL
D. 300 mL
10. The normal cerebrospinal fluid pressure in an adult human is approximately?
A. 25 mmHg
B. 15 – 20 mmHg
C. 5 mmHg
D. 10 mmHg