Chapter 6 Enzyme Converts Substrate Into Product This

Chapter 06 – Energy and Metabolism

Clarify Question

What is the key concept addressed by the question?

What type of thinking is required?

Gather Content

What do you already know about evolution and time? What other information is related to

the question?

Choose Answer

Do you have all necessary information to determine the relative importance of glycolysis

and the Kreb’s cycle?

Reflect on Process

Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Chapter 06 – Energy and Metabolism

46. Enzyme 1 converts substrate A into product B. Is this an example of a metabolic

pathway?

47. It is summer, and you are excited about going to your local amusement park, and

specifically about riding the new roller coaster that was just built. You imagine waiting at the

top of the stairs for the roller coaster to pull into the station, climbing into the car, strapping

yourself into the seatbelt, and pulling down the harness. You can imagine the cars slowly

chugging up to the top of the first hill, coming down on the other side, and the excitement you

expect to feel as you go along for the ride. Of all of the things that you have imagined, which

is an example of potential energy?

Chapter 06 – Energy and Metabolism

48. Phosphofructokinase (PFK) is an enzyme that converts fructose 6-phosphate to fructose

1,6-bisphosphate, by adding a phosphate group. This is the first committed step of the

metabolic pathway of glycolysis, and thus it is very tightly regulated. AMP binds to PFK at a

site distinct from the binding site for fructose 6-phosphate, and stimulates the formation of

fructose 1,6-bisphosphate. ATP binds to PFK at a site distinct from the binding site for

fructose 6-phosphate, and inhibits the formation of fructose 1,6-bisphosphate. There are other

regulators of this enzyme as well. What is the role of AMP in this example?

Chapter 06 – Energy and Metabolism

Clarify Question

What is the key concept addressed by the question?

What type of thinking is required?

Gather Content

What do you already know about enzymes, feedback inhibition, and glycolysis? What

other information is related to the question?

Choose Answer

Do you have all the information needed to determine how AMP helps to regulate PFK

activity?

Reflect on Process

Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

Chapter 06 – Energy and Metabolism

more desirable result?

49. You eat a bowl of beans as part of your dinner. As you digest the beans, the proteins that

are present get broken down to their component amino acids. As your body destroys the

macromolecules that were present in the beans, is the energy present in those molecules

destroyed?

50. While standing at the top of the stairs, you have a potential energy of 40 Joules. If you

walk all the way down the stairs, what would your potential energy be at the bottom of the

stairs?

Chapter 06 – Energy and Metabolism

Clarify Question

What is the key concept addressed by the question?

What type of thinking is required?

Gather Content

What do you already know about potential and kinetic energy? What other information is

related to the question?

Choose Answer

Do you have all the information needed to answer the question?

Reflect on Process

Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Chapter 06 – Energy and Metabolism

52. You return home to find that your baby brother has scattered his toy trains and trucks all

over the floor of your room. As you begin to pick up the toys and put them away, you realize

that even though he is just a baby, he has clearly mastered:

53. If the G of a reaction was -31.45 kJoules, you would know that:

Blooms Level: 2. Understand

Gradable: automatic

LO: 06.02.02 Relate free energy changes to the outcome of chemical reactions.

Section: 06.02

Topic: The Laws of Thermodynamics and Free Energy

54. In the hypothetical biochemical pathway, P → Q + R → S → T, which step is likely to

have evolved first?

Chapter 06 – Energy and Metabolism

Clarify Question

What is the key concept addressed by the question?

What type of thinking is required?

Gather Content

What do you already know about evolution? What other information is related to the

question?

Choose Answer

Do you have all necessary information to break down the biochemical pathway?

Reflect on Process

Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Chapter 06 – Energy and Metabolism

55. While conducting an experiment, you realize that a competitive inhibitor was interfering

with your reaction. How could you overcome this problem?

Chapter 06 – Energy and Metabolism

Clarify Question

What is the key concept addressed by the question?

What type of thinking is required?

Gather Content

What do you already know about enzymes and competitive inhibition? What other

information is related to the question?

Choose Answer

Do you have all the information needed to answer the question?

Reflect on Process

Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Chapter 06 – Energy and Metabolism

56. A ribozyme catalyzes a reaction on itself and actually changes shape. This is an example

of.