Chapter 56 Loss Dopaminergic Input From Substantia Nigra The

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Hall: Guyton and Hall Textbook of Medical Physiology, 12th Edition

Chapter 56: Contributions of the Cerebellum and Basal Ganglia to Overall Motor

Control

Test Bank

1. Which of the following are paired correctly?

A. Lateral cerebellar hemisphere – coordination of axial muscles

B. Spinocerebellum – sequencing and timing of motor movements

C. Purkinje cells – inhibitory input to deep nuclear cells of cerebellum

D. Cerebellar dysfunction – athetosis

2. Stimulation of a complex spike pattern in the Purkinje cells of the cerebellum can be

initiated by:

A. Stimulation of the inferior olivary complex

B. Stimulation of brain stem reticular nuclei

C. Stimulation of neurons in the red nucleus

D. Stimulation of the superior olivary complex

3. Neurological disease associated with the cerebellum produces which of the following

types of symptoms?

A. Resting tremor

B. Athetosis

C. Rigidity

D. Ataxia

4. Purkinje cell input to the deep nuclear cells of the cerebellum:

A. Is always stimulatory

B. Is always inhibitory

C. Is stimulatory only if it originates from the inferior olivary complex

D. Is stimulatory only if it originates from mossy fibers

5. Which circuit in the basal ganglia is thought to be involved in the cognitive control of

motor functions?

A. The caudate circuit

B. The putamen circuit

C. The Papez circuit

Test Bank

56-2

D. The nigropallidal thalamic circuit

6. Chorea and choreiform movement is a sign of dysfunction in which brain region?

A. The substantia nigra

B. The caudate nucleus and putamen

C. The subthalamic nucleus

D. The thalamus

7. Parkinson’s disease is the result of:

A. Disruption of the putamen circuit

B. Loss of GABA input from caudate nucleus and putaman to the substantia nigra

C. Loss of dopaminergic input from substantia nigra to the caudate nucleus and the

putamen

D. Loss of serotonin input from subtantia nigra to the thalamus and subthalamus

8. Efferent fibers from the cerebellum originate in:

A. The deep nuclear cell layer of the cerebellum

B. The Purkinje cell layer of the cerebellar cortex

C. The granular cell layer of the cerebellar cortex

D. The molecular cell layer of the cerebellar cortex

9. Neurological disease associated with the globus pallidus produces which type of

symptom?

A. Rigidity

B. Chorea

C. Hemiballismus

D. Athetosis

10. Which of the following structures IS NOT considered to be part of the basal ganglia?

A. The caudate nucleus

B. The red nucleus

C. The substantia nigra

D. The putamen

Test Bank

56-3

11. Hemiballismus is associated with damage or dysfunction of which of the following

structures?

A. The thalamus

B. The caudate nucleus

C. The subthalamus

D. The red nucleus

12. The structure in the motor system which compares intended motion with the actual

motion and initiates corrective changes if the two are mismatched is:

A. The flocculus of the cerebellum

B. The pontine reticular nuclei

C. The subthalamus

D. The inferior olive

13. The flocculonodular lobe of the cerebellum is associated most closely with:

A. The vestibular apparatus

B. The subthalamic nucleus

C. The rubrospinal tract

D. the superior olivary nucleus

14. Afferent signals from the periphery of the body travel to the cerebellum in which of the

following nerve tracts?

A. The ventral spinocerebellar tract

B. The fastigioreticular tract

C. The vestibulocerebellar tract

D. The reticulocerebellar tract