Hall: Guyton and Hall Textbook of Medical Physiology, 12th Edition
Chapter 34: Resistance of the Body to Infection: II. Immunity and Allergy Innate
Immunity
Test Bank
1. What occurs following presentation of antigen by an infected cell?
A. Generation of antibodies
B. Activation of cytotoxic T cells
C. Increase in phagocytosis
D. Release of histamine by mast cells
2. What is the term for adhesion of an invading microbe with IgG and complement to
facilitate recognition?
A. Chemokinesis
B. Opsonization
C. Phagolysosome fusion
D. Signal transduction
3. What causes the release of histamine in an allergic reaction?
A. The binding of IgM to basophils
B. The binding of IgE to mast cells
C. The release of histamine by helper T cells
D. The free radical stimulation of endothelial cells
4. Helper T-Cells:
A. Are identical to natural killer cells
B. Can be activated by the presentation of antigen by an infected cell
C. Require the presence of a competent B cell system
D. Destroy bacteria by phagocytosis
5. AIDS patients:
A. Will be able to generate a normal antibody response
B. Have normal T helper cells
C. Have an increased secretion of interleukins
D. Have a decrease in CD4+ cells
Test Bank
34-2
6. Presentation of antigen on MHC-I by a target cell will result in:
A. Generation of antibodies
B. Activation of cytotoxic T cells
C. Increase in phagocytosis
D. Release of histamine by mast cells
7. The marking of an invading microbe with IgG and complement to facilitate recognition is
referred to as:
A. Chemokinesis
B. Opsonization
C. Phagolysosome fusion
D. Signal transduction
8. Interleukin 2 (IL-2) is an important molecule in the immune response. What function
does it carry out?
A. Binds to and presents antigen
B. Causes proliferation of cytotoxic T cells
C. Kills virus-infected cells
D. Inhibits helper T-cells
9. Circulating antibodies are secreted mainly by:
A. T helper lymphocytes
B. T suppressor lymphocytes
C. Dormant B lymphocytes
D. Plasma cells
E. T killer lymphocytes
10. Tolerance to one’s own body is:
A. Due to lack of antigens on cells
B. Lack of receptors on lymphocytes to antigens
C. Loss of lymphocytes reactive to native antigens
D. Activation of suppressor cells
11. In sensitized persons, immediate hypersensitivity responses are primarily the result of
liberation of vasoactive substances by the action of which of the following?
A. Activated T lymphocytes on smooth muscle cells
B. IgA on basophils and mast cells
C. IgA on neutrophils and eosinophils
D. IgE on basophils and mast cells
E. IgE on neutrophils and eosinophils