Hall: Guyton and Hall Textbook of Medical Physiology, 12th Edition
Chapter 33: Resistance of the Body to Infection: I. Leukocytes, Granulocytes, the
Monocyte-Macrophage System, and Inflammation
Test Bank
1. How long do monocytes/macrophages remain in the tissue?
A. Several minutes
B. Several hours
C. Several days
D. Several months to years
2. A patient visits his physician for the examination of a sore on the patient’s lip. There was
no pain or drainage from the sore. The patient was subsequently admitted to the hospital
with a fever. His lab values were: HCT 34%, platelets 300,000/uL, WBC 4200/uL, with
68% lymphocytes, 20% neutrophils.
What is the diagnosis of this patient?
A. A mild, non-treatable, infection
B. Agranulocytosis
C. Aplastic anemia
D. Acute leukemia
E. Hemolytic anemia
3. A 20-year-old man presents to the emergency room with a two week history of diarrhea
following a trip out of the country. He is admitted to the hospital for dehydration. His
stool specimen is positive for parasitic eggs. Which type of WBCs would have an
elevated number?
A. Eosinophils
B. Neutrophils
C. T lymphocytes
D. B lymphocytes
E. Monocytes
4. What occurs following activation of basophils?
A. Decreased diapedesis of neutrophils
B. Decreased ameboid motion
C. Contraction of blood vessels
D. Increased capillary permeability
Test Bank
33-2
5. Neutrophils are capable of all of the following except?
A. Diapedesis
B. Phagocytosis of whole red blood cells
C. Ameboid motion
D. Production of proteolytic enzymes for digestion of bacteria
6. Which of the following is TRUE regarding white blood cells?
A. Granulocytes released from the bone marrow spend usually 10 to 20 days in the blood
before entering the interstitial tissues
B. Granulocytes are normally formed only in the bone marrow
C. There are more granulocytes in the bone marrow than in the entire blood
D. The concentration of neutrophils in the blood is half the concentration of lymphocytes
7. Adhesion of WBC to the endothelium is:
A. Due to a decrease in selectins
B. Dependent on activation of integrins
C. Due to the inhibition of histamine release
D. Greater on the arterial than venous side of the circulation
8. In a normal healthy person which of the following blood components has the longest life
span?
A. Macrophages
B. T cells
C. Erythrocytes
D. Platelets
9. Activation of basophils results in:
A. Decreased diapedesis of neutrophils
B. Decreased ameboid motion
C. The prevention of clotting to allow diapedesis
D. Decrease in capillary permeability
10. During an inflammatory response, which is the correct order for cellular events?
A. Infiltration of monocytes from blood, increased production of neutrophils, activation
of tissue macrophage, infiltration of neutrophils from the blood
B. Activation of tissue macrophage, infiltration of neutrophils from the blood,
infiltration of monocytes from blood, increased production of neutrophils
C. Increased production of neutrophils, activation of tissue macrophage, infiltration of
neutrophils from the blood, infiltration of monocytes from blood
D. Infiltration of neutrophils from the blood, activation of tissue macrophage, infiltration
of monocytes from blood, increased production of neutrophils
11. Basophils share functional and morphological characteristics with:
A. Monocytes
B. Macrophages
C. Mast cells
D. Myelocytes