Chapter 27 – Viruses
Chapter 27
Viruses
Multiple Choice Questions
1. A mutation in the gene encoding the integrase enzyme renders the protein non-functional.
How would this affect-the HIV infection cycle?
Chapter 27 – Viruses
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What is the key concept addressed by the question?
o This question addresses the HIV infection cycle.
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What type of thinking is required?
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What do you already know about the HIV infection cycle?
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
2. Vibrio cholerae lives in water and gets toxin genes from a virus by phage conversion. The
toxin kills the intestinal epithelial cells in the human host, resulting in massive diarrhea.
Untreated cholera has about a 50% mortality rate. How do the bacteria benefit?
Chapter 27 – Viruses
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What is the key concept addressed by the question?
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What type of thinking is required?
Gather Content
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What do you already know about cholera?
Choose Answer
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
3. Once a prophage is present in a bacterial genome, viral genes are reproduced every time
the bacterium multiplies. Expression of viral genes, however, is inhibited by a repressor
protein. Cell stress can induce the formation of proteases that degrade the repressor. What will
result?
Chapter 27 – Viruses
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What is the key concept addressed by the question?
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What type of thinking is required?
Gather Content
•
What do you already know about phage induction?
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•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
Chapter 27 – Viruses
4. What best describes whether a virus is likely to infect a particular cell?
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What do you already know about viral host range?
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•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
Blooms Level: 3. Apply
Gradable: automatic
LO: 27.01.02 Understand the basic mechanism of viral replication.
Section: 27.01 The Nature of Viruses
Topic: The Nature of Viruses
True / False Questions
5. Viruses are self-replicating but the replication is much faster in a host cell.
Multiple Choice Questions
6. An experimental chemical has been shown to selectively cleave phosphodiester bonds.
How would this affect a virus?
Chapter 27 – Viruses
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What do you already know about viral structure?
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
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Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
7. Can a virus be killed?
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What do you already know about viruses as organisms?
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
True / False Questions
8. Retroviruses are unique because they are a combination of RNA and DNA.
Multiple Choice Questions
9. What kind of pathogen would retain its ability to cause infections after being treated with
powerful proteolytic chemicals that would destroy all proteinaceous material?
Chapter 27 – Viruses
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What do you already know about viroids?
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likely to produce the correct answer?
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Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
10. A doctor’s office has run out of the latest flu vaccine, but many patients are asking for it.
One of the nurses finds some vials from last year’s batch in a refrigerator. Should they be
used?
Chapter 27 – Viruses
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What do you already know about the flu virus?
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
11. Which class of drugs would be effective against HIV but not against most other
pathogenic viruses?
Chapter 27 – Viruses
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•
What is the key concept addressed by the question?
•
What type of thinking is required?
Gather Content
•
What do you already know about HIV replication?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
True / False Questions
12. Nucleotide analogs are a class of drugs that are highly effective against many types of
viruses. They work by halting the replication of viral genes. They are equally effective at
stopping the spread of prion diseases.
Chapter 27 – Viruses
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What is the key concept addressed by the question?
•
What type of thinking is required?
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What do you already know about prions?
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Multiple Choice Questions
Chapter 27 – Viruses
13. Gardasil is marketed as a cervical cancer vaccine, but it is actually a human papilloma
virus (HPV) vaccine. Why is this done?
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What do you already know about the link between viruses and cancer?
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 27 – Viruses
14. If the gp120 glycoprotein were damaged as a result of a mutation, HIV would have
difficulty:
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
Gather Content
•
What do you already know about HIV infection?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?