Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about genome size?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 18 – Genomics
34. Your research group has recently determined the complete genomic sequence of the
organism Examus biologisium. You instruct your group to begin sequence annotation, which
involves
Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about genome analysis?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 18 – Genomics
35. The reason segmental duplications pose a logistical challenge in the proper alignment of
DNA sequences is that they
36. The best technique for detecting chromosomal abnormalities is
37. The organism with the largest relative genome size is
Chapter 18 – Genomics
38. When comparing the actual number of genes, the organism with the highest number is
39. In vertebrates, the family of myogenic regulatory factors (MRFs) plays a major role in
muscle development. This family consists of four related genes which have distinct but
overlapping functions. This gene family is represented by only a single gene in Drosophila,
called nautilus. You want to know whether nautilus plays a role like all of the MRFs put
together, or more like one in particular. What is a quick and easy way to begin to address this
question?
Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about sequence analysis?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
Chapter 18 – Genomics
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
40. As a scientist working for an anti-bioterrorism task force, you are asked to evaluate some
biological samples for the presence of Yersinia pestis, the organism that causes the plague.
After confirming that the samples do contain Y. pestis, you instruct your team to begin
sequencing the strain. Since the genome sequence of Y. pestis is already known, why would
sequencing this strain be useful?
Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about genome analysis?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
Chapter 18 – Genomics
more desirable result?
41. A pharmaceutical company is developing a new drug to treat a rare disease. They need to
determine which of the cell’s proteins can bind the drug. What tool can help them survey the
proteome for drug interactions?
Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about proteomics?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 18 – Genomics
42. How did the rice genome project influence other genome projects?
Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about the rice genome?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 18 – Genomics
43. You have been asked to construct a physical map of the baboon genome. What would be
helpful in this task?
Chapter 18 – Genomics
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about physical mapping?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
Chapter 18 – Genomics
Check All That Apply Questions
44. As the director of a new non-profit functional genomics research center, it is your job to
oversee the set up of each laboratory necessary for achieving the center’s research goals.
Therefore, you plan to include a (Select all that apply)
45. An accurate and comprehensive description of pseudogenes must include
46. The important advances stemming from comparative genomics include the ability to