Hall: Guyton and Hall Textbook of Medical Physiology, 12th Edition
Chapter 16: The Microcirculation and Lymphatic System: Capillary Fluid Exchange,
Interstitial Fluid, and Lymph Flow
Test Bank
1. Which one of the following substances in plasma does not contribute to plasma colloid
osmotic pressure?
A. Globulins
B. Fibrinogen
C. Albumin
D. NaCl
2. A decrease in arteriole diameter would most likely result in which of the following sets
of changes in a microcirculatory bed?
Interstitial Hydrostatic Capillary Hydrostatic Lymph
Pressure Pressure Flow
A.
B.
C.
D.
E.
F.
3. A decrease in which one of the following would tend to decrease filtration rate across a
capillary wall?
A. Plasma colloid osmotic pressure
B. Hydraulic conductivity of the wall
C. Plasma albumin concentration
D. Interstitial hydrostatic pressure
E. Arteriole resistance
4. Utilizing the data below, calculate the filtration coefficient for the capillary bed. (in
mL/min/mmHg):
Plasma colloid osmotic pressure = 30
Capillary hydrostatic pressure = 40
Interstitial hydrostatic pressure = 5
Interstitial colloid osmotic pressure = 5
Filtration rate = 150 mL/min
Test Bank
16-2
Venous hydrostatic pressure = 10 mmHg
A. 10
B. 15
C. 20
D. 25
E. 30
5. An increase in which one of the following would tend to decrease lymph flow?
A. Hydraulic conductivity of the capillary wall
B. Plasma colloid osmotic pressure
C. Capillary hydrostatic pressure
D. Precapillary arteriole diameter
E. Interstitial colloid osmotic pressure
6. Utilizing the data below, calculate the rate of net fluid movement (in mL/min) across the
capillary wall.
Plasma colloid osmotic pressure = 40 mmHg
Capillary hydrostatic pressure = 10 mmHg
Venous hydrostatic pressure = 5 mmHg
Arterial pressure = 80 mmHg
Interstitial hydrostatic pressure = 5 mmHg
Interstitial colloid osmotic pressure = 5 mmHg
Filtration coefficient = 10 mL/min/mmHg
A. 100 (Filtration)
B. 200 (Reabsorption)
C. 200 (Filtration)
D. 300 (Filtration)
E. 300 (Reabsorption)
7. Listed below are the hydrostatic and oncotic pressures across a muscle capillary wall.
Venous hydrostatic pressure = 5 mmHg
Arterial pressure = 100 mmHg
Capillary hydrostatic pressure = 35 mmHg
Plasma colloid osmotic pressure = 25 mmHg
Interstitial colloid osmotic pressure = 10 mmHg
Interstitial hydrostatic pressure = -5 mmHg
What is the net filtration pressure (in mmHg) for fluid movement across the capillary
wall?
A. 0
B. 5
Test Bank
16-3
C. 10
D. 15
E. 25
8. A decrease in which one of the following would tend to increase filtration rate across a
capillary wall?
A. Arterial pressure
B. Hydraulic conductivity of the wall
C. Interstitial albumin concentration
D. Capillary hydrostatic pressure
E. Arteriole resistance
9. Which of the following set of changes would be expected to increase the net movement
of sodium across a muscle capillary wall?
Wall Permeability Wall Surface Area Concentration Difference
to Sodium Across Wall
A.
B.
C.
D.
E.
F.
G.
H.
10. A healthy 20-year-old medical student has an exercise stress test. Which of the following
sets of changes would be expected to occur in the student’s skeletal muscles during
exercise?
Vascular Capillary Lymph
Resistance Hydrostatic Pressure Flow
A.
B.
C.
D.
E.
F.
G.
H.
Test Bank
16-4
11. Plasma colloid osmotic pressure:
A. Is less than interstitial colloid osmotic pressure
B. Decreases by 50% in the muscle capillaries as blood flows from the arteriole end to
the venous end
C. Is primarily caused by the presence of substances in the plasma such as sodium and
potassium
D. Increases in response to an increase in plasma albumin concentration
12. A 65-year-old woman has a 20-year history of alcoholism and liver disease. He visits his
physician complaining of swelling of his extremities. A decrease in which of the
following is one of the most likely cause of the ascites?
A. Capillary hydrostatic pressure
B. Arteriole conductance
C. Interstitial hydrostatic pressure
D. Plasma colloid osmotic pressure
E. Interstitial colloid osmotic pressure
13. An increase in which one of the following would tend to decrease filtration rate across a
capillary wall?
A. Arteriole diameter
B. Hydraulic conductivity of the wall
C. Interstitial albumin concentration
D. Capillary hydrostatic pressure
E. Plasma colloid osmotic pressure
14. An increase in which of the following would tend to decrease lymph flow?
A. Interstitial hydrostatic pressure
B. Plasma colloid osmotic pressure
C. Capillary hydrostatic pressure
D. Interstitial colloid osmotic pressure
E. Capillary hydraulic permeability