Chapter 16 – Control of Gene Expression
Clarify Question
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What is the key concept addressed by the question?
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What type of thinking is required?
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What key words does the question contain and what do they mean?
Gather Content
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What do you already know about prokaryotic transcriptional regulation?
Consider Possibilities
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Consider the different answer options. Which can you rule out?
Choose Answer
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Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
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Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 16 – Control of Gene Expression
38. The lactose analog isopropyl-beta-D-thio-galactoside (IPTG) is often used to regulate
gene expression systems in bacteria. IPTG does not act as a substrate for beta-galactosidase,
but can bind to, and inactivate, the repressor. In this case, IPTG serves as a(n)
Chapter 16 – Control of Gene Expression
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about prokaryotic transcriptional regulation?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 16 – Control of Gene Expression
39. The main form of glucose repression in the lac operon is
40. If you were given a bacterial strain with a mutation in the promoter region of the trp
operon the most likely effect would be
Chapter 16 – Control of Gene Expression
Clarify Question
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What is the key concept addressed by the question?
o This question addresses the promoter.
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What type of thinking is required?
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What key words does the question contain and what do they mean?
Gather Content
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What do you already know about promoters?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
Chapter 16 – Control of Gene Expression
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
41. You are studying regulation of a prokaryotic operon. Experiments show that expression
of the operon is increased when levels of biosynthetic product from that pathway are low.
Based on this information, what is a likely mode of regulation?
Chapter 16 – Control of Gene Expression
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about transcriptional regulation in prokaryotes?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Chapter 16 – Control of Gene Expression
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
42. The binding of TFIID is followed by the binding of a number of other general
transcription factors. The correct order of binding of these factors would be
43. Your research project involves the characterization of a recently identified transcription
factor. As part of your project, you want to determine if this transcription factor binds directly
to any of the general transcription factors. Unfortunately, you are having trouble expressing
Chapter 16 – Control of Gene Expression
Clarify Question
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What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about specific transcription factors?
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What other information is related to the question? Which information is most useful?
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Chapter 16 – Control of Gene Expression
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
44. You are working to identify enhancer regions of a particular gene. The best place to look
is
Chapter 16 – Control of Gene Expression
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you already know about enhancers?
Consider Possibilities
•
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Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 16 – Control of Gene Expression
45. The progesterone receptor (PR) is a steroid hormone receptor and transcription factor.
The protein SRC-1, which does not bind DNA by itself, can bind to PR and increase
expression of genes regulated by PR. Based on this information, SRC-1 is best described as
a(n)
Chapter 16 – Control of Gene Expression
Clarify Question
•
What is the key concept addressed by the question?
•
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•
What key words does the question contain and what do they mean?
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What do you already know about coactivators?
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Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
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Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 16 – Control of Gene Expression
46. The TFIID complex is formed by
47. The p300/CBP (CREB-binding protein) proteins are histone acetyltransferases that help
regulate the transcription of many genes. Based on this information you can conclude that
these proteins