Chapter 14 Mutation Produced Helicase That Was Unable

Chapter 14 – DNA: The Genetic Material

60. If a mutation produced helicase that was unable to hydrolyze ATP, DNA replication

would be

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about the function of helicase?

Consider Possibilities

• Consider the different answer options. Which can you rule out?

Choose Answer

Chapter 14 – DNA: The Genetic Material

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did

the process break down or lead you astray? How can you revise your approach to

produce a more desirable result?

61. Suppose a new species of bacterium is discovered. It contains a form of DNA pol III that

can add new nucleotides to either the 5′ end or the 3′ end of an existing strand. All other

properties of the enzyme remain unchanged. How would DNA replication in these bacteria

differ from normal replication?

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about DNA replication?

Consider Possibilities

• What other information is related to the question? Which information is most useful?

Choose Answer

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Chapter 14 – DNA: The Genetic Material

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

62. If 16% of the nucleotides in one strand of a DNA molecule contain the base G, what

percent of the nucleotides on the complementary strand will also contain the base G?

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about base pairing in DNA?

Consider Possibilities

• What other information is related to the question? Which information is most useful?

Choose Answer

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Reflect on Process

Chapter 14 – DNA: The Genetic Material

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

63. You decide to repeat the Meselson-Stahl experiment, except this time you plan to grow

the E. coli cells on light 14N medium for many generations and then transfer them to heavy

15N medium and allow them to grow for 2 additional generations (2 rounds of DNA

replication). If the conservative model of DNA replication was correct, what is the expected

distribution of DNA in the density gradient after two rounds of replication?

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about the Meselson-Stahl experiment?

Consider Possibilities

• What other information is related to the question? Which information is most useful?

Choose Answer

Chapter 14 – DNA: The Genetic Material

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

64. You decide to repeat the Meselson-Stahl experiment, except this time you plan to grow

the cells on light 14N medium for many generations and then transfer them to heavy 15N

medium and allow them to grow for 2 additional generations (2 rounds of DNA replication).

If the semiconservative model of DNA replication is correct, what is the expected distribution

of DNA in the density gradient after two rounds of replication?

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about the Meselson-Stahl experiment?

Consider Possibilities

• What other information is related to the question? Which information is most useful?

Choose Answer

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Chapter 14 – DNA: The Genetic Material

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Numeric Response Questions

65. You take a sample of bacteria with DNA that contains only 14N and allow them to

replicate in a medium that contains only 15N. After 3 rounds of replication, what percent of

the DNA molecules will contain one strand with only 14N and one strand with only

15N? Enter your answer as a whole number without the percent sign. For example, 5% would

be entered as 5 and 37% would be entered as 37.

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about the Meselson-Stahl experiment?

Consider Possibilities

• What other information is related to the question? Which information is most useful?

Choose Answer

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Chapter 14 – DNA: The Genetic Material

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Multiple Choice Questions

66. Genetic analysis indicates that an unknown organism contains a gene that codes for a

defective form of telomerase. Based on this information alone, you can conclude that this

organism

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about telomerase?

Consider Possibilities

• Consider the different answer options. Which can you rule out?

Choose Answer

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?

Chapter 14 – DNA: The Genetic Material

67. An organism has been found to contain a defective form of photolyase. What function

might be impaired in this organism?r

Chapter 14 – DNA: The Genetic Material

Clarify Question

• What is the key concept addressed by the question?

• What type of thinking is required?

• What key words does the question contain?

Gather Content

• What do you already know about photolyase?

Consider Possibilities

• Consider the different answer options. Which can you rule out?

Choose Answer

• Given what you now know, what information and/or problem solving approach is most

likely to produce the correct answer?

Reflect on Process

• Did your problem-solving process lead you to the correct answer? If not, where did the

process break down or lead you astray? How can you revise your approach to produce a

more desirable result?