Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
Chapter 13
Chromosomes, Mapping, and the Meiosis-Inheritance Connection
Multiple Choice Questions
1. A genetic _____ indicates the distances between gene loci measured in terms of the
frequency of recombination.
2. Of the 23 pairs of human chromosomes, 22 pairs are homologous and are found in both
males and females. These are called ________.
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
3. Traits that are controlled by genes located on the X chromosome are said to be
________________.
4. Allele pairs are most likely to assort independently of one another when
5. The number of allele pairs that assort independently in an organism is generally much
higher than the number of chromosome pairs. This phenomenon is due to
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
6. The theory of chromosomal inheritance was first proposed by
7. In Drosophila, the sex of an individual is determined by
8. In Morgan’s experiments, the white eye allele in Drosophila was shown to be
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
9. The geneticist who discovered the white eye mutation in Drosophila and helped establish
that genes are carried on chromosomes was
10. Genetic exchange between 2 homologous chromosomes is called
11. Occasionally, chromosomes fail to separate during meiosis, leading to daughter cells that
have an abnormal number of chromosomes. This phenomenon is called
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
12. Humans who have lost one copy of an autosome are called
13. In humans, individuals with trisomy of the ______ chromosome are most likely to
survive until adulthood.
14. If a human female has 2 Barr bodies per cell, it is almost certain that
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
15. A human female with only one X chromosome is said to have a condition called
16. The most common fatal genetic disorder of Caucasians is
17. In sickle cell anemia, the defective hemoglobin differs from the normal hemoglobin by
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
18. Hemophilia is caused by a
19. _______________ is a human hereditary disease that is caused by a dominant allele but
does not show up in affected individuals until they are in middle age.
20. Amniocentesis is a procedure that is normally used
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
21. Huntington’s disease is caused by a single dominant allele. It is a lethal disease, yet it
persists in the human population. Which of the following statements best describes why?
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain?
Gather Content
•
What do you already know about Huntington’s disease?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
22. In humans, the male has an X and a Y sex chromosome. The human female has two X
chromosomes. In birds, the female has a Z and a W sex chromosome while the male has two
Z chromosomes. Which of the following statements is accurate about which parent determines
the gender of the offspring based on inheritace of the necessary sex chromosome?
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain?
Gather Content
•
What do you already know about sex determination?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
environment, so we can rule out that option.
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
23. Sickle cell anemia is caused by a defect in the
24. How many Barr bodies does a normal human female contain in each diploid cell?
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
25. A test cross can be used to do all of the following except
26. Which of the following animals is a genetic male?
27. In humans, if non-disjunction led to an individual with a genotype of XO, that
person would
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
28. In humans, if non-disjunction led to an individual with a genotype of XXY, that
person would
29. Any genetic differences between individuals in a population are called
30. The classic experiments performed by Creighton and McClintock in Maize
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
31. In humans, if an XY individual had a deletion of the SYR gene, that person would
32. Which statement about calico cats is false?
33. If an XY human had a genetic disorder that causes insensitivity to androgens, that
person’s genotype and phenotype would be
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
34. Which offspring inherit all their mitochondrial DNA from their mother and none from
their father?
35. Nondisjunction of a single pair of autosomes can lead to all of the following except
36. If you needed to determine the order of genes on a chromosome, you should perform
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
37. A 39-year-old woman is in her sixth week of pregnancy. Due to her advanced age, she is
at higher risk for having a baby with Down’s syndrome than younger pregnant women. She
would like to find out as early as possible whether or not her baby has Down’s syndrome. Her
doctor should suggest
38. In Drosophila, dosage compensation is controlled by the male-specific lethal (MSL)
complex consisting of MSL proteins and roX RNAs. Based on what you know about dosage
compensation, the role of the MSL complex in males would be to
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
Clarify Question
•
What type of thinking is required?
•
What key words does the question contain?
Gather Content
•
What do you already know about dosage compensation?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
more desirable result?
In Drosophila, the allele red eyes (bw+) is dominant to the allele for brown eyes (bw). At another gene locus on the same
chromosome, the allele for thin wing veins (hv+) is dominant to the allele for heavy wing veins (hv). Flies homozygous
for bw and hv+ are crossed to flies homozygous for bw+ and hv to obtain doubly heterozygous F1 progeny.
39. Given that these two gene loci are very closely linked, the genotypic ratio in the F2
generation should be closest to
Chapter 13 – Chromosomes, Mapping, and the Meiosis-Inheritance Connection
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain?
Gather Content
•
What do you already know about genetic linkage?
Consider Possibilities
•
Consider the different answer options. Which can you rule out?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?