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1. The compound found in certain mushrooms used for their hallucinogenic effect is
a. phencyclidine.
b. psilocybin.
c. peyote.
d. ergot.
2. In 1943, scientist Albert Hoffman discovered LSD from
a. fenfluramine.
b. the belladonna plant.
c. a mushroom.
d. a rye fungus.
3. What is the most common route of administration for LSD?
a. Inhalation
b. Intranasally
c. Orally
d. Intravenously
4. LSD is chemically similar to which neurotransmitter?
a. Serotonin
b. GABA
c. Dopamine
d. Acetylcholine
5. CasereportssuggestthatusingLSDwith________mightbringonLSDrelated“flashbacks.”
a. benzodiazepines
b. barbiturates
c. SSRIs
d. aspirin
6. Rodney occasionally uses hallucinogens. At a party one night, he tells you he is feeling immense power and that his
arms are no longer connected to his body. Later that night, he seems extremely irritable and gets into a fight with
some of the other partygoers. Rodney is most likely using which of the following hallucinogens?
a. Phencyclidine
b. “Magicmushrooms”
c. MDMA
d. LSD
7. Gemma is at a party and tells you she is experiencing a profound sense of euphoria, extreme closeness to every
otherhumanandanimalontheplanet,andincreasedenergy.Shetellsyoushe’sneverfeltsogoodaboutherselfin
her life. You notice that she is sucking on a baby pacifier. Gemma is most likely using which of the following
hallucinogens?
a. Phencyclidine
b. “Magicmushrooms”
c. MDMA
d. LSD
8. The most common route of administration of MDMA is
a. inhaling.
b. intranasally.
c. orally.
d. intravenously.
9. There is controversy regarding whether MDMA causes long-term
a. dehydration.
b. heart disease.
c. hypothermia.
d. cognitive impairment.
10. According to your text, one plant with psychoactive effects not often thought of as falling into this category is
a. coca plants.
b. tobacco plants.
c. Aspen tree bark.
d. wild corn stalks.
11. Anthropologists believe that the peyote cactus has been used for religious ceremonies for at least
a. 15,000 years.
b. 12,000 years.
c. 8,000 years.
d. 4,000 years.
12. There are no known medical applications for any hallucinogens at this time. Which of the following statements is also
true?
a. There is ongoing research to determine whether there might possibly be a medicinal value to a compound in
natural hallucinogens.
b. The Drug Enforcement Administration is the main source of funding for such research, which means virtually
no research will be done in this area according to your text.
c. Their use as herbal medicines is limited to the indigenous peoples of Alaska.
d. There will never be any such research because of their status as agents used in religious ceremonies for
certain indigenous peoples in North America.
13. The“consentforparticipationinexperiment”formsthattheUnitedStatesArmyhadtestsubjectssignpriortotheir
involvement in experiments involving hallucinogens in the 1950s
a. were lost in the fires that resulted from the September 11 attack on the Pentagon.
b. did not ever exist.
c. were not specific to research involving chemical warfare agents; therefore, the recruits were entitled to
monetary settlement after a class action lawsuit.
d. were filled out and filed with the CIA, not the Army, and the CIA retains custody of these forms.
14. Approximately __________ compounds have been found in various plants that have a psychogenic effect:
a. 10,000
b. 50
c. 100
d. 1,000
15. LSD-induced hallucinations most commonly begin ______ after the compound is ingested by the user.
a. within 60 minutes
b. within 4 hours
c. within 12 hours
d. within 3-6 seconds
16. The lethal dosage level of LSD is
a. not known.
b. approximately 150 times the effective dose.
c. approximately 2,000 times the effective dose.
d. approximately 8,000 micrograms per kilogram of body weight.
17. According to your textbook, which of the following is NOT a likely consequence of PCP abuse?
a. Periodofweightgainafterrecoveryfromthedrug’seffects
b. Suicidal depression following PCP abuse
c. AssaultivenessduringtheacutephaseofPCP’seffects
d. Psychotic reaction
18. According to your text, phencyclidine tends to accumulate in
a. adipose tissues.
b. pancreatic tissues.
c. bone marrow.
d. blood vessel walls.
19. Which of the following is NOT one of the negative effects one could expect to experience in the first phase of the
LSD“trip?”
a. Tachycardia
b. Dilation of the pupils
c. Increased blood pressure
d. Hypersomnia
20. You know a friend recently ingested LSD. Your friend suddenly starts to cry uncontrollably. Based on your reading,
you would assume that your friend is in the ___ phase of the LSD experience.
a. third
b. first
c. second
d. fourth
21. Between______percentofLSDabuserswillexperienceatleastone“flashback”episode.
a. 12 and 22
b. 15 and 45
c. 15 and 77
d. 80 and 85
22. Oral doses of phencyclidine produce their first effects in
a. 30 minutes.
b. 2 minutes.
c. 2 hours.
d. 90 minutes.
23. A distorted sense of time is usually associated with a _______ of phencyclidine.
a. high dose of PCP (10 mg or higher)
b. oral dose
c. low dose of PCP (1-5 mg)
d. intermediate level dose (5-10 mg)
24. It is estimated that the worldwide annual production of MDMA is over
a. 4 metric tons.
b. 6 metric tons.
c. 8 metric tons.
d. 10 metric tons.
25. The effects of a single dose of MDMA are usually experienced within
a. 30-60 minutes.
b. 2 hours.
c. 90 minutes.
d. 3-4 minutes.
26. Since the time of its introduction, scientists have discovered that MDMA is a
a. mood stabilizer.
b. selective serotonin neurotoxin.
c. appetite suppressant.
d. compound useful in enhancing memory.
27. According to your text, MDMA abusers tend to
a. usually abuse MDMA continuously.
b. experience significant kidney problems.
c. interspace periods of active use with periods of abstinence.
d. use MDMA in isolation rather than in groups.
28. MDMA
a. hasanarrow“therapeutic”window,sothenormaldoseisclosetothetoxicdosagelevel.
b. has no effect on sleep apnea, and might even improve sleep respiration.
c. induces better interpersonal boundaries.
d. hasnoeffectontheindividual’sperceptionofexternalreality.
29. Describesomeofthevariouswayshallucinogeniccompoundshavebeenusedacrosstime.
30. DescribethetimecourseandsubjectiveeffectsofanLSD"trip."
31. Discuss the complications associated with PCP abuse, including how it can be an indirect cause of death.
32. ListanddescribethethreephasesofMDMA'ssubjectiveeffects.
33. Describe the history of the development of MDMA. Explain how it became popular as a recreational, though illicit,
drug.
34. ThereisnoriskofoverdosewithMDMA.
a. True
b. False
