Chapter 10 – How Cells Divide
45. Why is it so important that all of the chromosomes align on the metaphase plate during
metaphase?
46. If a cell was capable of bypassing metaphase and going directly from prometaphase to
anaphase, what is the most likely consequence of this?
Chapter 10 – How Cells Divide
Clarify Question
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What is the key concept addressed by the question?
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What type of thinking is required?
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What key words does the question contain and what do they mean?
Gather Content
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What do you know about metaphase? How does it relate to the question?
mitotic spindle.
Consider Possibilities
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What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 10 – How Cells Divide
47. Animal cells typically achieve cytokinesis by:
48. Plant cells typically achieve cytokinesis by:
49. If a drug that inhibited transport from the trans face of the Golgi was applied to plant
cells, which stage of the cell cycle would be directly affected?
Chapter 10 – How Cells Divide
Clarify Question
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What is the key concept addressed by the question?
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What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you know about the role of the Golgi in mitosis in plants? How does it relate to
the question?
Consider Possibilities
•
What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 10 – How Cells Divide
50. The progress of the eukaryotic cell cycle is regulated primarily by what proteins?
51. At what checkpoint(s) does the cell arrest in response to DNA damage?
52. You are examining the effect of maturation-promoting factor (MPF) in sea urchin cells,
which have a diploid number of 36. If you fuse a dividing sea urchin cell with a G1 arrested
oocyte, what would be the outcome?
Chapter 10 – How Cells Divide
Clarify Question
•
What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you know about MPF? How does it relate to the question?
Consider Possibilities
•
What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 10 – How Cells Divide
53. What time point represents G2?
54. You are studying cell cycle progression in yeast cells. If you could prevent cdc2 from
associating with the mitotic cyclin, the cells would:
Chapter 10 – How Cells Divide
Clarify Question
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What is the key concept addressed by the question?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you know about cdc2/cyclin complexes? How does it relate to the question?
Consider Possibilities
•
What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 10 – How Cells Divide
55. You are studying cell cycle progression in an early frog embryo. If you were to inject a
protein synthesis inhibitor into a cell during S phase, where do you predict that the cells
would arrest?
Chapter 10 – How Cells Divide
Clarify Question
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What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you know about protein synthesis and the cell cycle? How does it relate to the
question?
Consider Possibilities
•
What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 10 – How Cells Divide
56. In G2, there are typically high levels of the mitotic cyclin. Why is cdc2 not active during
G2 if the mitotic cyclin is present?
57. What is separase?
58. What is one of the roles of the APC/C during anaphase?
Chapter 10 – How Cells Divide
59. What would you expect to happen if the anaphase-promoting complex/cyclosome
(APC/C) failed to ubiquitinate securin?
Chapter 10 – How Cells Divide
Clarify Question
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What type of thinking is required?
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What key words does the question contain and what do they mean?
Gather Content
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What do you know about securin? How does it relate to the question?
ubiquitinate securin, then securin will remain active.
Consider Possibilities
•
What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
Chapter 10 – How Cells Divide
60. If you were to think of the cell as a car, and mitosis as a process that drives that car to go,
what would be a good analogy for a cell that has a mutation in both copies of a tumor-
suppressor gene?
Chapter 10 – How Cells Divide
61. You are leading a team of researchers at a pharmaceutical company. Your goal is to
design drugs that help fight cancer. Specifically, you want to focus on drugs that bind to and
inactivate certain proteins, thereby halting cell cycle progression. One of your team members
suggests targeting the retinoblastoma (Rb) protein and inhibiting this protein. Will this
approach be successful? Why or why not?
Chapter 10 – How Cells Divide
Clarify Question
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What is the key concept addressed by the question?
•
What type of thinking is required?
•
What key words does the question contain and what do they mean?
Gather Content
•
What do you know about Rb? How does it relate to the question?
Consider Possibilities
•
What other information is related to the question? Which information is most useful?
Choose Answer
•
Given what you now know, what information and/or problem solving approach is most
likely to produce the correct answer?
Reflect on Process
•
Did your problem-solving process lead you to the correct answer? If not, where did the
process break down or lead you astray? How can you revise your approach to produce a
more desirable result?
62. This protein or protein complex functions in the cell to stop cell division if the cell has
experienced extensive DNA damage:
Chapter 10 – How Cells Divide