In those parts of equatorial Africa where the malaria parasite is most common, the
sickle-cell allele constitutes 20% of the β hemoglobin alleles in the human gene pool.
In the United States, the parasite that causes malaria is not present, but
African-Americans whose ancestors were from equatorial Africa are present. What
should be happening to the sickle-cell allele in the United States, and what should be
happening to it in equatorial Africa?
A) stabilizing selection; disruptive selection
B) disruptive selection; stabilizing selection
C) directional selection; disruptive selection
D) directional selection; stabilizing selection
Use the following information to answer the question(s) below.
The following are an abstract and figure from a paper that explores the evolutionary
relationship between a protein kinase and behavior (M. Fitzpatrick and M. Sokolowski.
2004. In search of food: Exploring the evolutionary link between cGMP-dependent
protein kinase (PKG) and behavior. Integrative and Comparative Biology 44:28-36).
Abstract:
Despite an immense amount of variation in organisms throughout the animal kingdom,
many of their genes show substantial conservation in DNA sequence and protein
function. Here we explore the potential for a conserved evolutionary relationship
between genes and their behavioral phenotypes. We investigate the evolutionary history
of cGMP-dependent protein kinase (PKG) and its possible conserved function in
food-related behaviors. First identified for its role in the foraging behavior of fruit flies,
the PKG encoded by the foraging gene had since been associated with the maturation of
behavior (from nurse to forager) in honey bees and the roaming and dwelling
food-related locomotion in nematodes. These parallels encouraged us to construct
protein phylogenies using 32 PKG sequences that include 19 species. Our analyses
suggest five possible evolutionary histories that can explain the apparent conserved link
between PKG and behavior in fruit flies, honey bees, and nematodes. Three of these
raise the hypothesis that PKG influences the food-related behaviors of a wide variety of