Two students studying physiology taste a known “bitter” substance, and both report
sensing bitterness. They then sample another substance. Student A reports sensing both
a bitter taste and a salty taste, but student B reports only a salty taste. What is the most
logical explanation?
A) Student A had an allergic reaction to the food, causing him to perceive the food as
being bitter.
B) Student A has normal “bitter” taste buds; student B has defective “bitter” taste buds
that result in lower sensitivity to bitterness.
C) Student A has a protein receptor capable of detecting a bitter molecule found in that
substance, whereas student B lacks that particular protein receptor.
D) Student A has normal saliva, whereas student B’s saliva is more alkaline than
normal.
Rhodopsins are light-sensitive molecules composed of a protein (opsin) and retinal
(derivative of vitamin A). Opsin is a membrane protein with several α-helical segments
that loop back and forth through the plasma membrane. There are two classes of
rhodopsins. According to Oded Beje, one class has relatively slow dynamics (a
photocycle of approximately 0.5 second) and is well suited for light detection. The
second class has faster dynamics (a photocycle of approximately 0.02 seconds) and is
well suited for chemiosmosis: pumping of protons or chloride ions across cell
membranes. Oded Beje was the first, in September 2000, to report on a rhodopsin
(proteorhodopsin) found in the domain Bacteria. [SOURCE: O. Beje et al., Science 289
(2000): 1902.]
Proteorhodopsin consists of a single polypeptide chain. What is the highest level of
structure found in this protein?
A) primary
B) secondary
C) tertiary
D) quaternary