Which of the following calculations require that you utilize the addition rule?
A) Calculate the probability of black offspring from the cross AaBb x AaBb, where B is
the symbol for black.
B) Calculate the probability of children with both cystic fibrosis and polydactyly when
parents are each heterozygous for both genes.
C) Calculate the probability of each of four children having cystic fibrosis if the parents
are both heterozygous.
D) Calculate the probability of a child having either sickle-cell anemia or cystic fibrosis
if parents are each heterozygous for both.
For a science fair project, two students decided to repeat the Hershey and Chase
experiment, with modifications. They decided to label the nitrogen of the DNA, rather
than the phosphate. They reasoned that each nucleotide has only one phosphate and two
to five nitrogens. Thus, labeling the nitrogens would provide a stronger signal than
labeling the phosphates. Why won’t this experiment work?
A) There is no radioactive isotope of nitrogen.
B) Radioactive nitrogen has a half-life of 100,000 years, and the material would be too
dangerous for too long.
C) Although there are more nitrogens in a nucleotide, labeled phosphates actually have
sixteen extra neutrons; therefore, they are more radioactive.
D) Amino acids (and thus proteins) also have nitrogen atoms; thus, the radioactivity
would not distinguish between DNA and proteins.