“Marine cone snails from the genus Conus are estimated to consist of up to 700 species.
These predatory molluscs have devised an efficient venom apparatus that allows them
to successfully capture polychaete worms, other molluscs, or in some cases fish as their
primary food sources. conotoxins from Australian species of Conus have the capacity to
inhibit specifically the nicotinic acetylcholine receptors in higher animals.” (B. G.
Livett, K. R. Gayler, and Z. Khalil. 2004. Drugs from the sea: Conopeptides as potential
therapeutics. Current Medicinal Chemistry 11:1715-23.)
Refer to the paragraph above on the venom of marine core snails. This particular
conotoxin inhibits acetylcholine receptors that are located _____.
A) along the motor neuron axon
B) on motor neuron dendrites
C) on the presynaptic membrane of the neuromuscular junction
D) on the postsynaptic membrane, on the muscle cell
The crucian carp (Carassius carassius) is a Northern European freshwater fish often
inhabiting ponds that become hypoxic (have reduced oxygen levels) and even anoxic
(have no oxygen) when the surface freezes during the winter. Surprisingly, when
oxygen levels are normal, these fish lack the lamellae that provide a large surface area
for gas exchange between water and blood: their gills are smooth. Yet when the level of
oxygen in the water falls, the gill morphology undergoes a change: packing cells stop
dividing and programmed cell death is induced, exposing gill lamellae that were buried
in other tissue. With lamellae exposed, the gills have increased surface area for gas
exchange. These changes in gill lamellar profile are reversible: investigators observed