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Describe the conceptual basis for constructing biochemical pathways using nutrient
supplement experiments with Neurospora.
List the components of a nucleosome.
List, in order, the steps usually followed in producing recombinant DNA molecules in a
plasmid vector.
The finding that virtually all organisms use the same genetic code provides the basis for
declaring that the code is universal. Name at least two exceptions to such universality.
The horse (Equus caballus) has 32 pairs of chromosomes, whereas the donkey (Equus
asinus) has 31 pairs of chromosomes. How many chromosomes would be expected in
the somatic tissue of a mule?
Contrast directional and stabilizing forms of selection.
Describe the relationship between introns (size and number) and organismic complexity
in eukaryotes.
What is meant by the equation p + q = 1.0?
In a population of cattle, the following color distribution was noted: 36% red (RR), 48%
roan (Rr), and 16% white (rr). Is this population in a Hardy-Weinberg equilibrium?
What will be the distribution of genotypes in the next generation if the Hardy-Weinberg
assumptions are met?
Briefly describe general trends relating to DNA content and gene number in major
groups of organisms.
What is comparative genomics?
Compare the rate of DNA replication in prokaryotes and eukaryotes.
What is a mutation?
Interpret the meaning of an H2 (broad-sense heritability) value that approaches 1.0.
Name at least three applications for examining sequence variants such as RFLPs.
As unwinding of the helix occurs during DNA replication, tension is created ahead of
the replication fork. Describe the nature of this tension and state the manner in which
this tension is resolved.
Assuming independent assortment, what proportion of the offspring of the cross
will have the aabbccdd genotype?
