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What is ELSI?
How many Barr bodies would one expect to see in cells of Turner syndrome females
and Klinefelter syndrome males?
Given that the origin of replication is fixed in E. coli, what signals the location of the
origin?
Which would change allele frequencies more quickly: selection against a dominant
allele or selection against a recessive allele?
What process is effectively the true test of the functionally synthetic genome?
Until the mid-1940s, many scientists considered proteins to be the likely candidates for
the genetic material. Why?
Assume that a cross is made between two organisms that are both heterozygous for a
gene that shows incomplete dominance. What phenotypic and genotypic ratios are
expected in the offspring?
Provide a brief description of the variable gene activity hypothesis as it relates to
development. What information is often provided in support of this hypothesis?
Homologous chromosomes are those that can be matched by virtue of their similar
structure and function within a nucleus. Which chromosomes making up a genome do
not follow the same characteristics of homology?
Suppose that the dinucleotide in the accompanying figure was cleaved with the enzyme
spleen diesterase, which breaks the covalent bond connecting the phosphate to C-5".
After such cleavage, to which nucleoside is the phosphate now attached?
If one is attempting to determine the influence of genes or the environment on
phenotypic variation, inbred strains with individuals of a relatively homogeneous or
constant genetic background are often used. Variation observed between different
inbred strains reared in a constant or homogeneous environment would likely be caused
by genetic factors. What would be the source of variation observed among members of
the same inbred strain reared under various environmental conditions?
Is the accompanying figure DNA or RNA? Is the circle closer to the 5" or 3" end?
What is a simple definition of an allele?
The following F2 results occur from a typical dihybrid cross:
purple: A_B_ 9/16
white: aaB_ 3/16
white: A_bb 3/16
white: aabb 1/1
If a double heterozygote (AaBb) is crossed with a fully recessive organism (aabb), what
phenotypic ratio is expected in the offspring?
Under what condition might a human female have the XY sex chromosome
complement?
Beatrice Mintz and others microinjected DNA into a fertilized mouse egg, which after
reaching maturity could be transmitted to the mouse's offspring. What is the general
term used to describe an organism that incorporates foreign DNA?
