Recent genetic studies of the structure of microsporidian genomes, as well as the
sequences of their tubulin genes and the gene for RNA polymerase II, indicate that
microsporidians are closely related to the fungi. Microsporidians lack flagella,
centrioles, peroxisomes, and mitochondria (although they do have degenerate
mitochondria, called mitosomes). They have the smallest genome of any eukaryote, and
it is a genome that changes quickly. The genome is contained within two haploid nuclei.
All microsporidians are obligate intracellular parasites. They use a unique organelle
called a polar filament to gain access to the cells of their hosts. One species causes
chronic diarrhea in AIDS patients. Another parasitizes Anopheles gambiae, the
mosquito that transmits a fatal form of malaria to humans.
Given the eukaryotic structures they lack, it should be expected that microsporidians
also lack _____.
A) the “9 + 2 pattern” of microtubules
B) centrosomes
C) lysosomes
D) nuclei
Zoonotic disease _____.
A) is caused by suborganismal pathogens such as viruses, viroids, and prions only
B) is caused by pathogens that are transferred from other animals to humans by direct
contact or by means of a vector
C) can only be spread from animals to humans through direct contact
D) can only be transferred from animals to humans by means of an intermediate host