BISC 45805

subject Type Homework Help
subject Pages 6
subject Words 641
subject Authors Charlotte A. Spencer, Michael A. Palladino, Michael R. Cummings, William S. Klug

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What are LINES?
In what way can loss of heterozygosity lead to cancer?
Data produced by C. Bridges in the early part of this century indicate that sex in
Drosophila is determined by ________.
The white-eye gene in Drosophila is recessive and sex-linked. Assume that a
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white-eyed female is mated to a wild-type male. What would be the phenotypes of the
offspring?
What is a merozygote?
Would one expect a linear relationship between DNA sequence divergence and
phylogenetic distance? Why or why not?
Regarding the protein structure, how are β-pleated sheets arranged and stabilized?
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After which meiotic stage (meiosis I or II) would one expect monads to be formed?
Monod discovered that if tryptophan is present in relatively high quantities in the
growth medium, the enzymes necessary for its synthesis are repressed. How does this
occur?
Describe the difference between a focused promoter and a dispersed promoter.
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Describe the molecular and transmission characteristics of Leber's hereditary optic
neuropathy (LHON).
Assume that a dihybrid F2 ratio, resulting from epistasis, was 9:3:4. If a double
heterozygote was crossed with the fully recessive type, what phenotypic ratio is
expected among the offspring?
What explanation is generally given for lethality of monosomic individuals?
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Describe an experiment in which transgenic mice were used to identify the
male-determining region of the Y chromosome.
A certain form of albinism in humans is recessive and autosomal. Assume that 1% of
the individuals in a given population are albino. Assuming that the population is in
Hardy-Weinberg equilibrium, what percentage of the individuals in this population is
expected to be heterozygous?
Explain the goal of the emerging discipline called systems biology.
Which three classes of macromolecules are encoded by mtDNA?

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