BI 94316

subject Type Homework Help
subject Pages 7
subject Words 943
subject Authors Charlotte A. Spencer, Michael A. Palladino, Michael R. Cummings, William S. Klug

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The relationship between codon and anticodon can be characterized as involving
________.
A certain type of congenital deafness in humans is caused by a rare autosomal dominant
gene. In a mating involving a deaf man and a deaf woman, could all the children have
normal hearing? Explain your answer.
Arabidopsis is a model organism for the study of ________.
Over the years, sophisticated plasmid vectors have been developed for use in
recombinant DNA technology. List at least two features that have been introduced in
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particularly useful vectors.
Define the term fitness and relate it to the meaning of selection coefficient.
How are gene therapy and recombinant DNA technology related?
When propagating a clone in the lambda phage, would you have more immediate
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success if the phage entered the lysogenic or the lytic cycle?
What is the probability of flipping a penny and a nickel and obtaining one head and one
tail?
Molecular biologists rely on many, often sophisticated, techniques to pursue their
discipline. One may list ultracentrifugation, electron microscopy, X-ray diffraction,
electrophoresis, and computer interfacing as fundamental tools. Model organisms
provide the raw materials for study. List three "organisms" (or organismic groups) often
used by recombinant DNA technologists and describe a major advantage of each group.
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Assume that a cross is made between AaBb and aabb plants and that the offspring occur
in the following numbers: 106 AaBb, 48 Aabb, 52 aaBb, 94 aabb. These results are
consistent with what arrangement of genes?
In what way is gene rearrangement related to gene regulation? Give an example.
Why are some proteins more likely than others to diverge within a species?
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What conditions are likely to apply if the progeny from the cross AaBb x AaBb appear
in the 9:3:3:1 ratio?
The accompanying figure diagrams DNA replication as currently believed to occur in
E. coli. From specific points, arrows lead to numbers. Answer the questions relating to
the locations specified by the numbers.
(1) Which end (5" or 3") of the molecule is here?
(2) Which enzyme is probably functioning here to deal with supercoils in the DNA?
(3) Which enzyme is probably functioning here to unwind the DNA?
(4) Which nucleic acid is probably depicted here?
(5) What are these short DNA fragments usually called?
(6) Which enzyme probably functions here to couple these two newly synthesized
fragments of DNA?
(7) Is this strand the leading or lagging strand?
(8) Which end (5" or 3") of the molecule is here?
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In instances in the eukaryotic genome, DNA sequences represent evolutionary vestiges
of duplicated copies of genes. What are such regions called and what are their
characteristics?
The human metallothionein IIA gene (hMTIIA) is transcriptionally regulated through
the interplay of regulatory elements and transcription factors. What is the function of
this gene, and how is it regulated by environmental circumstances?
How many different alleles can a gene have?

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