A phenotypically normal prospective couple seeks genetic counseling because the man
knows that he has a translocation of a portion of his chromosome 4 that has been
exchanged with a portion of his chromosome 12. Although his translocation is
balanced, he and his wife want to know the probability that his sperm will be abnormal.
What is your prognosis regarding his sperm?
A) 1/4 will carry the two normal chromosomes, 4 and 12, 1/4 will have only the two
translocation chromosomes and no normal chromosomes 4 and 12, and 1/2 will have
both normal and translocated chromosomes.
B) All will carry the same translocation as the father.
C) None will carry the translocation.
D) 1/2 will be normal and the rest will have the father’s translocation.
A mutation that inactivates a regulatory gene of a repressible operon in an E. coli cell
would result in _____.
A) continuous transcription of the structural gene controlled by that regulator
B) complete inhibition of transcription of the structural gene controlled by that
regulator
C) irreversible binding of the repressor to the operator
D) continuous translation of the mRNA because of alteration of its structure