1.Thedose-dependenteffectoftheearlyanxiolytic/hypnoticdrugsmeanstheycouldproduce__________intheuser.
a.sedation
b.sleep
c.death
d.allofthese
ANSWER: d
POINTS: 1
REFERENCES: EarlyMedicalTreatmentofAnxietyandInsomnia
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
2.BromidesaltsarenolongeravailableforhumanuseintheUnitedStates,buttheycontinuetobeusedinveterinary
medicine.
a.True
b.False
ANSWER: True
POINTS: 1
REFERENCES: EarlyMedicalTreatmentofAnxietyandInsomnia
QUESTIONTYPE:True/False
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
3.Barbituratesareusedaspartofthelethalinjectionforthedeathpenalty.
a.True
b.False
ANSWER: True
POINTS: 1
REFERENCES: HistoryandCurrentMedicalUsesofBarbiturates
QUESTIONTYPE:True/False
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
4.Whenbarbituratemoleculesarecirculatedthroughoutthebody,thehighestconcentrationsarefoundinthe_______.
a.kidneyandstomach
b.pancreasandduodenum
c.spleenandgallbladder
d.liverandbrain
ANSWER: d
POINTS: 1
REFERENCES: PharmacologyoftheBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
5.Theuseofbarbituratesisdiscouragedbecauseof________.
a.theirnarrowtherapeuticwindow
b.theirinefficacyasasedativeorahypnoticdrug
c.theirhighlethalityinoverdosesituations
d.theirnarrowtherapeuticwindowandhighlethalityinoverdosesituations
ANSWER: d
POINTS: 1
REFERENCES: PharmacologyoftheBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
6.Jorgehasjustdiscontinueduseofbarbituratesthathewasusingregularlytohelphimsleep.Heislikelytoexperience
_____.
a.deepersleepthaneverbefore
b.REMrebound
c.alackofdreamsduringhissleep
d.decreasedanxiety
ANSWER: b
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
7.Individualswithproblemswiththeir________areespeciallyatriskofexperiencing“barbituratehangovers.”
a.liver
b.kidney
c.heart
d.lungs
ANSWER: a
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
8.BarbituratesarehelpfultopeoplewithADHD.
a.True
b.False
ANSWER: False
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:True/False
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
9.Barbituratesshouldnotbemixedwith______.
a.alcohol
b.MAOinhibitors
c.antihistamines
d.alloftheseanswersarecorrect
ANSWER: d
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
10.Whenanindividualoverdosesonabarbiturate,theywillmostlikelyexperience_____.
a.astroke
b.respiratorydepression
c.amanicepisode
d.aseizure
ANSWER: b
POINTS: 1
REFERENCES: EffectsoftheBarbituratesatAbove-NormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
11.Barbituratewithdrawalispotentiallylifethreateningandshouldonlybeattemptedunderthecareofaphysician.
a.True
b.False
ANSWER: True
POINTS: 1
REFERENCES: Neuroadaptation,Tolerance,andPhysicalDependenceonBarbiturates
QUESTIONTYPE:True/False
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
12.Whichofthefollowingstatementsismostaccurateoftheanxietydisorders?
a.Theyarecollectivelythemostcommonformofpsychiatricdiagnosis.
b.Theyarethethirdmostcommonformofpsychiatricdiagnosisafterdepressionandpsychoticdisorders.
c.Theyhavenorelationshiptothesufferers’lifestyles.
d.Theyarealwaysreflectedinobsessive-compulsivedisorders.
ANSWER: a
POINTS: 1
REFERENCES: Introduction
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
13.EachyearintheU.S.,approximately__________ofthepopulationwillexperienceatleasttransitorysymptomsof
insomnia.
a.33percent
b.10percent
c.50percent
d.25percent
ANSWER: a
POINTS: 1
REFERENCES: Introduction
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
14.Accordingtoyourtext,thefirstuseofchloralhydratewasas________.
a.paincontrol
b.ahypnoticagent
c.treatmentforinsomnia
d.arecreationaldrug
ANSWER: b
POINTS: 1
REFERENCES: EarlyMedicalTreatmentofAnxietyandInsomnia
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
15.Whichofthefollowingisoneofthemajordisadvantagesofparaldehyde?
a.Cardio-suppressanteffects
b.Noxioustasteandodoronbreath
c.Stainingpropertiesontheuser’steeth
d.Addictiveeffects(abouthalfthoseof)alcohol
ANSWER: b
POINTS: 1
REFERENCES: EarlyMedicalTreatmentofAnxietyandInsomnia
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
16.Thebromidesaltswereinitiallyintroducedasa__________.
a.treatmentforinsomnia,andlater,whenitwasdiscoveredtheyalsohaveantiseizureeffects,asan
anticonvulsant
b.treatmentforepilepsy,andlaterasasedativeandhypnotic
c.treatmentforgastricdistresscausedbyimpurewater,untilitwasdiscoveredtheyhadantiseizureeffects
d.methodofself-discoverybyElizabethandrugabusers
ANSWER: b
POINTS: 1
REFERENCES: EarlyMedicalTreatmentofAnxietyandInsomnia
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
17.Whenusedathigherthanrecommendeddoses,diphenhydraminecaninduceastateof________inolderadults.
a.impairedhearing
b.tardivedyskinesia
c.delirium
d.anemia
ANSWER: c
POINTS: 1
REFERENCES: EarlyMedicalTreatmentofAnxietyandInsomnia
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
18.Barbituricacidhasbeenfoundtobe_________.
a.apotenthallucinogenic
b.twiceasstrongasdiazepamasananxiolyticcompound
c.difficulttodigestwhenconsumedwithfoodsthatarehighlyacidic
d.biologicallyinactive
ANSWER: d
POINTS: 1
REFERENCES: HistoryandCurrentMedicalUsesofBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
19.Attheheightoftheirpopularity_________.
a.morethanonemillionpoundsofbarbituratecompoundsweremanufacturedintheUnitedStateseachyear
b.morethanonemillionpoundsofbarbituratecompoundsweremanufacturedglobally
c.barbiturateswereonlyalaboratorycuriosityforchemists,withoutmedicalapplication
d.barbiturateswereneverrejectedasanagentforlethalinjection
ANSWER: a
POINTS: 1
REFERENCES: HistoryandCurrentMedicalUsesofBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
20.Whichofthefollowingstatementsismosttrue?
a.Barbituratescontinuetobearelativelypopulardrugofabuse.
b.Somephysiciansarenowstartingtoprescribebarbituratestoavoidthepaperworkassociatedwiththe
prescriptionofothercontrolledcompounds.
c.Barbituratesarefrequentlyabusedbyprofessionalfootballplayersforthedrug’sabilitytocontrolthestress
thattheyexperienceinmajorgames.
d.Barbituratesareaminoringredientof“energydrinks”tocounteracttheeffectsofthecaffeinethataretheir
maincomponent.
ANSWER: b
POINTS: 1
REFERENCES: HistoryandCurrentMedicalUsesofBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
21.Accordingtoyourtext,thebarbiturates_________.
a.haveaverylimitedroleinmodernmedicine
b.typicallyexacerbateseizuredisordersinpatientspredisposedtosuchconditions
c.arenotcontraindicatedforcommercialorcivilianpilots
d.arethedrugofchoicefortheaggressivetreatmentofGABA/NMDAinhibitiondisorders
ANSWER: a
POINTS: 1
REFERENCES: HistoryandCurrentMedicalUsesofBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
22.Followingmedicalconvention,yourtextgroupsthebarbituratestogetheronthebasisoftheir________.
a.degreeofNMDAantagonisticaction
b.abilitytoforcetheGABAaionchanneltoremainopen
c.abilitytoenhancetheeffectsofGABAaatthereceptorsite
d.durationofaction
ANSWER: d
POINTS: 1
REFERENCES: PharmacologyoftheBarbiturates
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
23.A(n)_______________isoccasionallyencounteredafterapatienttakesabarbiturate,evenatrecommended
doses.
a.increaseinheartratetopossiblydangerouslevels
b.paradoxicalincreaseinthetawaveactivityontheEEGwhilethepatientisawake
c.increaseinrespirationtopossiblyfatallevels
d.paradoxicalragereaction
ANSWER: d
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
24.Barbituratescan_____________whenusedasahypnotic.
a.causeaparadoxicalincreaseinthetawaveactivityontheEEGwhilethepatientisasleep
b.causeanincreasein“spindles”and“spikes”seenontheEEGduringstage2sleep
c.helptheuserpassfromstage1tostage2sleepmoreeasily
d.suppressthedurationofnormalREMsleep
ANSWER: d
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
25.Barbituratescan_________.
a.induceanamphetamine-likestateofmania
b.inducerespirationarrestathighdosagelevels
c.increaserespirationtothepointatwhichittriggersananxietyattackinpersonswithADHD
d.notinducetolerance
ANSWER: b
POINTS: 1
REFERENCES: EffectsoftheBarbituratesatAbove-NormalDosageLevels
QUESTIONTYPE:MultipleChoice
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
26.Discussthehistoricalandcurrentmedicalusesofbarbiturates.Includeareviewofthemisusepotentialofthese
drugs.
ANSWER: Noanswerprovided.
POINTS: 1
REFERENCES: HistoricalandCurrentMedicalUsesofBarbiturates
QUESTIONTYPE:Essay
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
27.Compareandcontrastthedifferentclassificationsofbarbituratesandnotetheprimarycriterionthatdistinguishesone
groupfromanother.
ANSWER: Noanswerprovided.
POINTS: 1
REFERENCES: PharmacologyoftheBarbiturates
QUESTIONTYPE:Essay
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
28.Discusssomeofthesubjectiveeffectsofbarbituratesatnormaldosagelevels.
ANSWER: Noanswerprovided.
POINTS: 1
REFERENCES: SubjectiveEffectsofBarbituratesatNormalDosageLevels
QUESTIONTYPE:Essay
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
29.Whataresomeofthepotentialdruginteractionsinvolvingbarbiturates?
ANSWER: Noanswerprovided.
POINTS: 1
REFERENCES: ComplicationsofBarbiturateUseatNormalDosageLevels
QUESTIONTYPE:Essay
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM
30.Describesomeofthebarbiturate-likedrugsthathavedevelopedsincethe1950s.Whyweretheydeveloped?
ANSWER: Noanswerprovided.
POINTS: 1
REFERENCES: TheBarbiturate-LikeDrugs
QUESTIONTYPE:Essay
HASVARIABLES: False
DATECREATED: 2/21/20181:34PM
DATEMODIFIED:2/21/20181:37PM