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Question:Syphilis
Answer: In advanced syphilis, a bacterial microorganism enters the brain and
causes delusions of persecution, delusions of grandeur. Patients would
deteriorate steadily, becoming paralyzed and dying w/in 5 years of onset→ in
1825 it was designated the disease of general paresis
Patients with malaria recovered more so than others , the fever “burned out”
the bacteria causing the psychosis– disease linked to curable infection
Penicillin late discovered as the cure
Question:John P. Grey
Answer: Most influential American psychiatrist of the time. Held that the
causes for insanity were always physical→ therefore, mentally ill patients
Should be treated as physically ill→ conditions in hospitals improved and they
became more humane institutions, however they became so large that
individual treatment was often impossible
Question:Development of Biological Treatments
Answer: 1930s electro shock therapy & brain surgery were often used
Insulin shock therapy used to induce convulsions in patients, many recovered
their mental health but many others died or became comatose
Electroconvulsive therapy→ Hungarian physician Jospeh von Meduna in the
1920s suggested that induced brain seizures could cure schizophrenia, 6 small
shocks delivered to the brain has been known to cure patients
1950s→ use of sedative medicines were employed
• fauwolfia serpentine (reserpine) & neuroleptics, and benzodiazepines