Dq2
Clinical significance refers to how important a therapeutic effect is in whether it has a real,
tangible, and visible impact on everyday life. In clinical research, statistically significant study
findings are often regarded as clinically significant. Clinical significance represents the study’s
effect on clinical practice, while statistical significance demonstrates the study’s trustworthiness.
Treatment effect size is one of the most significant variables that drive treatment decisions, and
its implications or current practice determines its clinical importance. The research sample size
determines statistical significance; with high sample sizes, even minor treatment effects may
seem statistically significant.
Clinical significance is a method of evaluating intervention study findings beyond NHST and
