Mood disorders: involve disabling disturbances in emotion, from sadness of depression to elation and
irritability of mania. Panic attacks, substance abuse, sexual dysfunction, personality disorders.
Depression: emotional state marked by great sadness and feelings of worthlessness and guilt. Withdrawl
from others, loss of sleep, appetite, sexual desire, and interest in usual activities.
– Paying attention is exhausting; cannot converse, speak slowly, monotonous, prefer loneliness,
some agitated and cannot sit still, neglect hygiene, anixious, apprehensive
– In children: somatic complaints ie. Headaches
– In adults: distractibility
– Cross-cultural differences due to standards of acceptable behaviour (less prevalent in China,
cannot show emotion)
Psychologizers (Kirmayer): people who emphasize psychological aspect of depressed rather than the
physical somatic aspect.
Mania: emotional state of intense but unfounded elation accompanied by irritability, hyperactivity,
talkativeness, flight of ideas, distractibility, and impractical, grandiose plans. (side effect of depression)
– Manic episodes, incoherent shift of topic to topic, overly sociable and intrustive, oblivious to
pitfalls of their behaviour.
– Attempt to curb this behaviour can elicit rage
2 major mood disorders in DSM-5: major depressive and dipolar disorder (now has separate chapters for
it) – Bipolar disorder is a bridge between two diagnostic classes of schizophrenia spectrum disorders
and depressive disorders in terms of symptomatology, family history and genetics.
Diagnosis of depression: requires presence of five of following symptoms for at least two weeks.
– Depressed mood/loss of interest and pleasure must be one
– Sad, depressed mood most of day nearly every day
– Difficulty sleeping
– Shift inactivity level (lethargic or agitated). Psychomotor agitation of retardation.
– Poor appetite, weight loss or vise versa
– Loss of energy and fatigue every day
– Negative self concept, self blame, feelings of worthlessness and blame
– Difficulty concentrating, slowed thinking, indecisiveness
– Thoughts of death/suicide
Controversial: whether person with five symptoms and two week duration is different from one who has
three symptoms for 10 days.
– Using twin studies: less than five symptoms and duration less than two weeks, more likely to be
diagnosed with depression and have recurrences.
– Depression exists on continuum of severity, DSM classified those with MDD at severe end
– Question of whether diagnosis should be by category or by continuum.
– Broad spectrum of severity: not all individuals require intensive treatment
Persistent depressive disorder: chronic depression and dysthymia.
Predictors: comorbid diagnosis. Younger age of onset, history of more frequent episode of depression.
– MDD two times more common women than men; gender gap emerges at age 14.
– WHO identified MDD as one leading cause of disability-adjusted life years. First in disease
burden in high income countries by year 2030.