Name_____________________ No._________
Written Assignment #1 key
1. Identify the four categories of pathogens that provoke immune responses in our bodies that we mentioned in class. For each category, give one example of an organism and the disease they cause. Is your example an intracellular or extracellular pathogen?
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2. What is hematopoiesis and where does it take place in adults?
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3. What is an antigen? An antibody? Where the antibody produced? What is the relationship between antigen and antibody?
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4. Do the following apply to innate immune mechanisms? Explain.
A) absence of specificity
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B) broad recognition of pathogens
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C) involvement of multiple cell types
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D) a memory component
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5. Immediately following a break in the skin, phagocytes engulf bacteria within the wound. This is an example of an _________ immune response which is __________ against a pathogen.
A) adaptive, specific
B) innate, specific
C) innate, nonspecific
D) adaptive, nonspecific
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6. ____________ is responsible for the production of antibody against free pathogens and soluble products from pathogens while ____________ destroy pathogen and virally infected cells and abnormal cells.
A) Cytotoxic T cells, B cells
B) Macrophages, T cells
C) B cells, helper T cells
D) B cells, cytotoxic T cells
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7. What is opsonization?
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8. What is clonal selection and clonal expansion?
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9. What is the difference in function between primary and secondary lymphoid tissues?
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10. Compare and contrast innate and adaptive immunity by matching the following characteristics with the correct arm of immunity, using “I” for innate and “A” for
adaptive:
a. Is the first to engage upon initial encounter with antigen
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b. Is the most pathogen specific
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c. Employs T and B lymphocytes
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d. Adapts during the response
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e. Responds almost identically during first and second response
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f. Responds more effectively during subsequent exposure
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g. Includes a memory component
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h. Is the target of vaccination
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i. Involves antigen-specific receptors binding to pathogens
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